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Viral load and Integration status of High-Risk Human Papillomaviruses in the Barrett's metaplasia–dysplasia–adenocarcinoma sequence


Wang, B and Rajendra, S and Pavey, D and Sharma, P and Merrett, N and Wu, X and Snow, ET and Kumbhari, V and Ball, MJ and Robertson, IK, Viral load and Integration status of High-Risk Human Papillomaviruses in the Barrett's metaplasia-dysplasia-adenocarcinoma sequence, American Journal of Gastroenterology, 108, (11) pp. 1814-1816. ISSN 0002-9270 (2013) [Refereed Article]

Copyright Statement

Copyright 2013 American College of Gastroenterology

DOI: doi:10.1038/ajg.2013.206


Recently, we demonstrated a strong association of transcriptionally active high-risk human papillomavirus (hr-HPV) with Barrett ’ s dysplasia (BD) and esophageal adenocarcinoma (EAC) (1). To further clarify the role of hr-HPV infection in the Barrett ’ s metaplasia – dysplasia – adenocarcinoma sequence, esophageal specimens positive for hr-HPV-16 or hr-HPV-18 DNA obtained from 83 patients (mostly recruited from our previous study) (1) were utilized to assess viral load and integration status.

Item Details

Item Type:Refereed Article
Keywords:Barrett's Oesophagus, Human Papilloma Virus, Gastroesophageal cancer
Research Division:Biomedical and Clinical Sciences
Research Group:Oncology and carcinogenesis
Research Field:Cancer genetics
Objective Division:Health
Objective Group:Clinical health
Objective Field:Clinical health not elsewhere classified
UTAS Author:Snow, ET (Associate Professor Elizabeth Snow)
UTAS Author:Ball, MJ (Professor Madeleine Ball)
UTAS Author:Robertson, IK (Dr Iain Robertson)
ID Code:89466
Year Published:2013
Web of Science® Times Cited:23
Deposited By:Health Sciences A
Deposited On:2014-03-05
Last Modified:2018-03-22

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