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Clinical predictors of severe acute pancreatitis: value-adding the view from the end of the bed

journal contribution
posted on 2023-05-17, 21:52 authored by Richard TurnerRichard Turner, McDermott, R

Background: Research into clinical determinants of severe acute pancreatitis remains important for therapeutic and preventive purposes. To contribute to prognostication, this study aimed to define clinical risk factors for the development of severe acute pancreatitis.

Methods: Study design was a prospective cohort study, using multiple logistic regression. From March 2004 to July 2007, 153 cases of acute pancreatitis were recruited in a regional Australian hospital. Data were collected regarding demographic and clinical characteristics. The outcome measure was severe acute pancreatitis, as defined by composite consensus criteria.

Results: After adjustment for potential confounders, there was a significant positive association with waist circumference and a negative association with current smoking status.

Conclusion: The study confirms other work suggesting central adiposity as a risk factor for severe acute pancreatitis. The finding of a possible protective effect for smoking may be physiologically plausible but merits further confirmatory research.

History

Publication title

A N Z Journal of Surgery

Volume

84

Issue

9

Pagination

672-676

ISSN

1445-1433

Department/School

Tasmanian School of Medicine

Publisher

Blackwell Publishing Asia

Place of publication

54 University St, P O Box 378, Carlton, Australia, Victoria, 3053

Rights statement

Copyright 2013 Royal Australasian College of Surgeons

Repository Status

  • Restricted

Socio-economic Objectives

Clinical health not elsewhere classified

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