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Approaches to Enhancing the Sensitivity of Carbohydrate Separations in Capillary Electrophoresis
Citation
Breadmore, MC, Approaches to Enhancing the Sensitivity of Carbohydrate Separations in Capillary Electrophoresis, Capillary Electrophoresis of Biomolecules: Methods and Protocols, Humana Press, N Volpi and F Maccari (ed), New York, USA, pp. 27-43. ISBN 978-1-62703-295-7 (2013) [Research Book Chapter]
Copyright Statement
Copyright 2013 Springer Science+Business Media
DOI: doi:10.1007/978-1-62703-296-4_3
Abstract
Electrophoresis in both capillaries (CE) and microchips (ME) is an extremely powerful liquid phase-separation technique that is indispensable for the separation of carbohydrates. It is capable of separating both small mono- and disaccharides, through to more complex oligo- and polysaccharides, with high resolution, but as with all CE and ME separations, the detection limits are often inferior to those that can be achieved with liquid chromatographic methods. One avenue to address this is to use an on-line concentration strategy. Various approaches have been developed over the past 20 years, and this chapter will highlight their application to improve the sensitivity of carbohydrate separations in both CE and ME.
Item Details
| Item Type: | Research Book Chapter |
|---|---|
| Keywords: | electrophoresis, carbohydrates |
| Research Division: | Chemical Sciences |
| Research Group: | Analytical Chemistry |
| Research Field: | Separation Science |
| Objective Division: | Expanding Knowledge |
| Objective Group: | Expanding Knowledge |
| Objective Field: | Expanding Knowledge in the Chemical Sciences |
| UTAS Author: | Breadmore, MC (Professor Michael Breadmore) |
| ID Code: | 88422 |
| Year Published: | 2013 |
| Funding Support: | Australian Research Council (DP0984745) |
| Deposited By: | Austn Centre for Research in Separation Science |
| Deposited On: | 2014-02-03 |
| Last Modified: | 2014-08-25 |
| Downloads: | 0 |
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