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Childhood lifestyle and clinical determinants of adult ideal cardiovascular health. The Cardiovascular Risk in Young Finns Study, the Childhood Determinants of Adult Health Study, the Princeton Follow-up Study

Citation

Laitinen, TT and Pahkala, K and Venn, A and Woo, JG and Oikonen, M and Dwyer, T and Mikkila, V and Hutri-Kahonen, N and Smith, KJ and Gall, SL and Morrison, JA and Viikari, JSA and Raitakari, OT and Magnussen, CG and Juonala, M, Childhood lifestyle and clinical determinants of adult ideal cardiovascular health. The Cardiovascular Risk in Young Finns Study, the Childhood Determinants of Adult Health Study, the Princeton Follow-up Study, International Journal of Cardiology, 169, (2) pp. 126-132. ISSN 0167-5273 (2013) [Refereed Article]

Copyright Statement

Copyright 2013 Elsevier Ireland Ltd.

DOI: doi:10.1016/j.ijcard.2013.08.090

Abstract

Background: The American Heart Association recently defined ideal cardiovascular health by simultaneous presence of seven health behaviors and factors. The concept is associated with cardiovascular disease incidence, and cardiovascular disease and all-cause mortality. To effectively promote ideal cardiovascular health already early in life, childhood factors predicting future ideal cardiovascular health should be investigated. Our aim was thus to comprehensively explore childhood determinants of adult ideal cardiovascular health in population based cohorts from three continents. Methods: The sample comprised a total of 4409 participants aged 3-19 years at baseline from the Cardiovascular Risk in Young Finns Study (YFS; N = 1883) from Finland, Childhood Determinants of Adult Health Study (CDAH; N = 1803) from Australia and Princeton Follow-up Study (PFS; N = 723) from the United States. Participants were re-examined 19-31 years later when aged 30-48 years. Results: In multivariable analyses, independent childhood predictors of adult ideal cardiovascular health were family socioeconomic status (P < 0.01; direct association) and BMI (P < 0.001; inverse association) in all cohorts. In addition, blood pressure (P = 0.007), LDL-cholesterol (P < 0.001) and parental smoking (P = 0.006) in the YFS, and own smoking (P = 0.001) in CDAH were inversely associated with future ideal cardiovascular health. Conclusions: Among several lifestyle and clinical indicators studied, higher family socioeconomic status and non-smoking (parental/own) in childhood independently predict ideal cardiovascular health in adulthood. As atherosclerotic cardiovascular diseases are rooted in childhood, our findings suggest that special attention could be paid to children who are from low socioeconomic status families, and who smoke or whose parents smoke, to prevent cardiovascular disease morbidity and mortality. © 2013 Elsevier Ireland Ltd. All rights reserved.

Item Details

Item Type:Refereed Article
Keywords:Children, Cardiovascular diseases, Epidemiology, Risk factors, Prevention
Research Division:Medical and Health Sciences
Research Group:Public Health and Health Services
Research Field:Epidemiology
Objective Division:Health
Objective Group:Clinical Health (Organs, Diseases and Abnormal Conditions)
Objective Field:Cardiovascular System and Diseases
Author:Venn, A (Professor Alison Venn)
Author:Smith, KJ (Dr Kylie Smith)
Author:Gall, SL (Dr Seana Gall)
Author:Magnussen, CG (Dr Costan Magnussen)
ID Code:87794
Year Published:2013
Funding Support:National Health and Medical Research Council (1037559)
Web of Science® Times Cited:38
Deposited By:Menzies Institute for Medical Research
Deposited On:2013-12-06
Last Modified:2017-11-03
Downloads:0

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