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Multiplexed dual second-dimension column comprehensive two-dimensional gas chromatography (GC x 2GC) using thermal modulation and contra-directional second-dimension columns

Citation

Savareear, B and Shellie, RA, Multiplexed dual second-dimension column comprehensive two-dimensional gas chromatography (GC x 2GC) using thermal modulation and contra-directional second-dimension columns, Analytica Chimica Acta, 803 pp. 160-165. ISSN 0003-2670 (2013) [Refereed Article]

Copyright Statement

Copyright 2013 Elsevier B.V.

DOI: doi:10.1016/j.aca.2013.05.013

Abstract

A multiplexed dual-secondary column comprehensive two-dimensional gas chromatography approach (GC × 2GC) designed for complex sample analysis is introduced. The approach splits the first-dimension column effluent into two second-dimension columns with different stationary phases, and recombines the two streams into one detector post-separation. The approach produces two single two-dimensional chromatograms for each injection. Careful manipulation of thermal modulator timing parameters combined with a novel contra-directional modulation regime facilitates this approach. A selection of 34 laboratory reference compounds containing n-alkanes, alcohols, aromatic hydrocarbons, ketones, esters and halogenated hydrocarbons were analysed to demonstrate the approach. The dual two-dimensional chromatogram from this single detector system provides complementary information due to the unique selectivity of the three separation columns. The results of this proof-of-principle investigation provide significant impetus for further development of GC × 2GC–MS methodology.

Item Details

Item Type:Refereed Article
Keywords:gas chromatography, comprehensive two-dimensional, dual second-dimension columns, multiplexed, contra-directional
Research Division:Chemical Sciences
Research Group:Analytical Chemistry
Research Field:Separation Science
Objective Division:Expanding Knowledge
Objective Group:Expanding Knowledge
Objective Field:Expanding Knowledge in the Chemical Sciences
Author:Savareear, B (Mr Benjamin Savareear)
Author:Shellie, RA (Associate Professor Robert Shellie)
ID Code:87724
Year Published:2013
Web of Science® Times Cited:5
Deposited By:Austn Centre for Research in Separation Science
Deposited On:2013-12-04
Last Modified:2017-10-31
Downloads:0

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