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The Pattern of Breathing in Acute Severe Asthma


Hillman, DR and Prentice, L and Finucane, KE, The Pattern of Breathing in Acute Severe Asthma, The American review of respiratory disease, 133, (4) pp. 587 - 592. ISSN 0003-0805 (1986) [Refereed Article]


The pattern of breathing was studied in 8 patients with acute severe asthma on admission to hospital and during recovery to determine how chest wall motion varied with the degree of air-flow obstruction (AO), the relationship between degree of AO and respiratory timing and ventilation, and whether the pattern suggested respiratory muscle fatigue when asthma was most severe. Pattern was assessed by simultaneous measurement of respired volumes (pneumotachygraph) and anteroposterior (AP) motion of lower rib cage and abdomen (magnetometers). There was a phase lag of AP rib cage relative to AP abdominal motion that was greatest in those with lowest FEV1 and progressively decreased during recovery. Fractional inspiratory time was decreased in severe asthma. Mean inspiratory flow was increased in moderately severe asthma but decreased when FEV1 was less than 25% predicted. Breathing pattern was no more variable during severe asthma than during recovery. We conclude that during severe AO the magnitude of phase lag of AP rib cage relative to AP abdominal motion reflects severity of asthma; respiratory drive is increased but is not associated with increased ventilation below an FEV1 of 25% predicted, and analysis of the breathing pattern provides no clear evidence of respiratory muscle fatigue.

Item Details

Item Type:Refereed Article
Research Division:Biomedical and Clinical Sciences
Research Group:Cardiovascular medicine and haematology
Research Field:Respiratory diseases
Objective Division:Health
Objective Group:Clinical health
Objective Field:Clinical health not elsewhere classified
UTAS Author:Prentice, L (Dr Louise Prentice)
ID Code:87028
Year Published:1986
Web of Science® Times Cited:32
Deposited By:Medicine
Deposited On:2013-11-06
Last Modified:2013-11-06

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