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Fluid recovery during lung lavage in meconium aspiration syndrome


Dargaville, PA and Copnell, B and Mills, JF and Haron, I and Lee, JKF and Tingay, DG and Rohana, J and Mildenhall, LF and Jeng, M-J and Narayanan, A and Battin, MR and Kuschel, CA and Sadowsky, JL and Patel, H and Kilburn, CJ and Carlin, JB and Morley, CJ, on behalf of the lessMAS Trial Study Group, Fluid recovery during lung lavage in meconium aspiration syndrome, Acta Paediatrica, International Journal of Paediatrics, 102, (2) pp. e90-e93. ISSN 0803-5253 (2013) [Refereed Article]

Copyright Statement

Copyright 2012 The Authors, Acta Pædiatrica, Foundation Acta Pædiatrica

DOI: doi:10.1111/apa.12070


Lung lavage using two aliquots of 15 mL/kg of dilute surfactant was performed in 30 ventilated infants with severe meconium aspiration syndrome (MAS). Mean recovery of instilled lavage fluid was 46%, with greater fluid return associated with lower mean airway pressure at 24 h and a shorter duration of respiratory support.

Conclusion: Recovery of instilled lavage fluid is paramount in effective lung lavage in MAS and must be afforded priority in the lavage technique.

Item Details

Item Type:Refereed Article
Keywords:Lung lavage, Meconium aspiration syndrome, Pulmonary surfactants
Research Division:Biomedical and Clinical Sciences
Research Group:Paediatrics
Research Field:Paediatrics not elsewhere classified
Objective Division:Health
Objective Group:Clinical health
Objective Field:Clinical health not elsewhere classified
UTAS Author:Dargaville, PA (Professor Peter Dargaville)
ID Code:86091
Year Published:2013
Web of Science® Times Cited:8
Deposited By:Menzies Institute for Medical Research
Deposited On:2013-08-22
Last Modified:2019-07-30

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