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Preparation of some angularly substituted and highly functionalized quinolizidines as building blocks for the synthesis of various alkaloids and related scaffolds of medicinal interest

Citation

Bissember, AC and Banwell, MG, Preparation of some angularly substituted and highly functionalized quinolizidines as building blocks for the synthesis of various alkaloids and related scaffolds of medicinal interest, Tetrahedron, 65, (39) pp. 8222-8230. ISSN 0040-4020 (2009) [Refereed Article]

Copyright Statement

Copyright 2009 Elsevier

DOI: doi:10.1016/j.tet.2009.07.067

Abstract

The epimeric forms of the angularly substituted quinolizidine 6, representing potentially useful building blocks for the synthesis of various alkaloids, have been prepared via a pathway involving two consecutive ring-closing metathesis reactions. Variously hydroxy-protected derivatives (21, 22, and 2629) of these compounds have also been generated.

Item Details

Item Type:Refereed Article
Keywords:Alkaloids; Fasicularin; Quinolizidines; Ring-closing metathesis; Vinylation
Research Division:Chemical Sciences
Research Group:Organic Chemistry
Research Field:Organic Chemical Synthesis
Objective Division:Expanding Knowledge
Objective Group:Expanding Knowledge
Objective Field:Expanding Knowledge in the Chemical Sciences
Author:Bissember, AC (Dr Alex Bissember)
ID Code:85974
Year Published:2009
Web of Science® Times Cited:4
Deposited By:Chemistry
Deposited On:2013-08-19
Last Modified:2015-02-13
Downloads:0

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