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Capillary electrophoresis for monitoring bioprocesses

journal contribution
posted on 2023-05-17, 18:37 authored by Alhusban, AA, Michael BreadmoreMichael Breadmore, Rosanne Guijt
Chemical characterization and monitoring of fermentation broths and cell culture media provide significant information on the changes occurring within these complex and dynamic systems. Analytical methods based on CE in capillaries and microchips are attractive for integration in instrumental tools to obtain this critical data, improving the understanding and control of bioprocesses. In this review, the use of CE for chemical characterization and monitoring fermentations is discussed, organized by analyte class, including organic acids, pharmaceuticals, proteins, sugars, amino acids, and metabolites published between 1992 and October 2012. A section is dedicated to the roles CE plays throughout the wine making process, where applications range from characterization and increase in fundamental understanding of the fermentation to forensic applications, verifying the authenticity of the wine.

History

Publication title

Electrophoresis

Volume

34

Issue

11

Pagination

1465-1482

ISSN

0173-0835

Department/School

School of Pharmacy and Pharmacology

Publisher

Wiley-V C H Verlag Gmbh

Place of publication

PO Box 10 11 61, Weinheim, Germany, D-69451

Rights statement

Copyright 2013 WILEY-VCH

Repository Status

  • Restricted

Socio-economic Objectives

Expanding knowledge in the chemical sciences

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