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Imaging and diagnostic criteria for Multiple Sclerosis: Are we there yet?


Josey, L and Curley, M and Jafari Mousavi, F and Taylor, BV and Lucas, R and Coulthard, A, Imaging and diagnostic criteria for Multiple Sclerosis: Are we there yet?, Journal of Medical Imaging and Radiation Oncology, 56, (6) pp. 588-593. ISSN 1754-9477 (2012) [Contribution to Refereed Journal]

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DOI: doi:10.1111/j.1754-9485.2012.02448.x


Introduction: Excluding post traumatic injury, Multiple Sclerosis (MS) is the most common disabling neurological disorder of young adults. Although the effect on mortality is limited, the association of a young demographic and significant morbidity combine to make MS a devastating disease. Since MS was given its first detailed description in 1868, diagnostic criteria continue to evolve. Recently, there has been an international commitment to combine both clinical and paraclinical tests to arrive at an earlier diagnosis. Widespread acceptance of the use of MRI in diagnosis, monitoring and research has made the role of the radiologist more critical than ever in this disease. The primary diagnostic criteria for MS are the International Panel criteria, commonly referred to as the McDonald criteria and it is essential that the radiology community is aware of the work preceding these criteria, so that they are understood in the correct context and the importance acknowledged.

Methods: Literature review utilising key word search to obtain the historical and current context of magnetic resonance imaging in the diagnosis of MS.

Results: A succinct description of the evolution of criteria for the diagnosis of MS.

Conclusions: Radiologists must recognise that there are specific diagnostic criteria for MS that continue to evolve as a result of new research, improved technology and clinical experience and it is crucial that these criteria be applied in daily practice. It should be evident that diagnostic imaging criteria for MS will be most effective when combined with standardised MRI protocols such as those published by the international Consortium of Multiple Sclerosis Centres.

Item Details

Item Type:Contribution to Refereed Journal
Keywords:adult, humans, magnetic resonance imaging, multiple sclerosis, diagnosis, neurology
Research Division:Biomedical and Clinical Sciences
Research Group:Immunology
Research Field:Autoimmunity
Objective Division:Health
Objective Group:Clinical health
Objective Field:Clinical health not elsewhere classified
UTAS Author:Taylor, BV (Professor Bruce Taylor)
ID Code:85086
Year Published:2012
Web of Science® Times Cited:1
Deposited By:Research Division
Deposited On:2013-06-13
Last Modified:2013-06-14

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