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A retrospective study on the use of heparin for peripheral vascular intervention


Walker, S and Beasley, C and Reeves, M, A retrospective study on the use of heparin for peripheral vascular intervention, Perspectives in Vascular Surgery and Endovascular Therapy, 24, (2) pp. 63-69. ISSN 1531-0035 (2012) [Refereed Article]

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Copyright 2012 The Author(s)

DOI: doi:10.1177/1531003512459889


Purpose: To compare immediate outcomes for patients who receive and those who do not receive heparin during lower limb endovascular intervention.

Methods: A retrospective case series of 330 procedures for lower limb peripheral arterial occlusive disease. Patient records were interrogated for bleeding or thrombotic/embolic complications during or immediately after endovascular intervention for peripheral arterial occlusive disease.

Results: Of the 220 patients who received heparin, 21 (9.6%) suffered an access site bleed compared with 2 of the 110 patients (2%) who did not receive heparin (odds ratio [OR] = 5.7; 95% confidence interval [CI] = 1.3-25; P =.01). There were 6 embolic/thrombotic complications in the patients who received heparin (2.7%) compared with 4 in those that did not receive heparin (3.6%; P =.74). In 187 cases, a closure or compression device was used (StarClose, n = 109; Angio-Seal, n = 42; FemoStop, n = 35; ProGlide, n = 1), of which there were 3 access bleeding complications (2%). One hundred and forty-three cases did not have a closure or compression device associated with 17 (12%) access bleeding complications (OR = 0.25; 95% CI = 0.09-0.64; P =.004).

Conclusions: In this study, heparin use and nonuse of a closure or compression device was associated with an increased risk of access site bleeding. Embolic/thrombotic complications were uncommon.

Item Details

Item Type:Refereed Article
Keywords:anticoagulation, angioplasty, peripheral stent
Research Division:Biomedical and Clinical Sciences
Research Group:Clinical sciences
Research Field:Clinical sciences not elsewhere classified
Objective Division:Health
Objective Group:Clinical health
Objective Field:Diagnosis of human diseases and conditions
UTAS Author:Reeves, M (Dr Mark Reeves)
ID Code:84931
Year Published:2012
Deposited By:Rural Clinical School
Deposited On:2013-06-06
Last Modified:2013-07-09

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