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Echium oil is better than rapeseed oil in improving the response of barramundi to a disease challenge

journal contribution
posted on 2023-05-17, 18:10 authored by Alhazzaa, R, Andrew BridleAndrew Bridle, Mori, TA, Barden, AE, Nichols, PD, Christopher CarterChristopher Carter
Pathogen infection stimulates the fatty acid (FA) metabolism and the production of pro-inflammatory derivatives of FA. Barramundi, Lates calcarifer, was fed on a diet rich in preformed long-chain (PC20) polyunsaturated fatty acids (LC-PUFA) from fish oil (FO), to compare with diets containing high levels of C18 precursors for LC-PUFA – stearidonic (SDA) and c-linolenic acid (GLA) – from Echium plantagineum (EO), or rapeseed oil (RO) rich in a-linolenic acid (ALA), but a poor source of LC-PUFA and their precursors. After 6 weeks, when growth rates were similar amongst the dietary treatments, a sub-lethal dose of Streptococcus iniae was administered to half of the fish, while the other half were maintained unchallenged and were pair-fed with the infected fish. Under a disease challenge situation, the tissue FA depots depleted at 3 days post-infection (DPI) and were then restored to their previous concentrations at 7 DPI. During the infection period, EO fish had a higher content of n3 and n6 PUFA in their tissues, higher n3:n6 PUFA ratio and reduced levels of the eicosanoids, TXB2 and 6-keto-PGF1a, in their plasma compared with RO fish. Fish fed on FO and EO had a longer lasting and enduring response in their FA and eicosanoid concentrations, following a week of bacterial infection, compared with those fed on RO. EO, containing SDA and GLA and with a comparatively higher n3:n6 PUFA ratio, proved more effective than RO in compensating for immunity stress.

History

Publication title

Food Chemistry

Volume

141

Pagination

1424-1432

ISSN

0308-8146

Department/School

Institute for Marine and Antarctic Studies

Publisher

Elsevier Sci Ltd

Place of publication

The Boulevard, Langford Lane, Kidlington, Oxford, England, Oxon, Ox5 1Gb

Rights statement

Copyright 2013 Elsevier Ltd.

Repository Status

  • Restricted

Socio-economic Objectives

Aquaculture crustaceans (excl. rock lobster and prawns)

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