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Echium oil is better than rapeseed oil in improving the response of barramundi to a disease challenge

Citation

Alhazzaa, R and Bridle, AR and Mori, TA and Barden, AE and Nichols, PD and Carter, CG, Echium oil is better than rapeseed oil in improving the response of barramundi to a disease challenge, Food Chemistry, 141, (2) pp. 1424-1432. ISSN 0308-8146 (2013) [Refereed Article]

Copyright Statement

Copyright 2013 Elsevier Ltd.

DOI: doi:10.1016/j.foodchem.2013.04.052

Abstract

Pathogen infection stimulates the fatty acid (FA) metabolism and the production of pro-inflammatory derivatives of FA. Barramundi, Lates calcarifer, was fed on a diet rich in preformed long-chain (PC20) polyunsaturated fatty acids (LC-PUFA) from fish oil (FO), to compare with diets containing high levels of C18 precursors for LC-PUFA – stearidonic (SDA) and c-linolenic acid (GLA) – from Echium plantagineum (EO), or rapeseed oil (RO) rich in a-linolenic acid (ALA), but a poor source of LC-PUFA and their precursors. After 6 weeks, when growth rates were similar amongst the dietary treatments, a sub-lethal dose of Streptococcus iniae was administered to half of the fish, while the other half were maintained unchallenged and were pair-fed with the infected fish. Under a disease challenge situation, the tissue FA depots depleted at 3 days post-infection (DPI) and were then restored to their previous concentrations at 7 DPI. During the infection period, EO fish had a higher content of n3 and n6 PUFA in their tissues, higher n3:n6 PUFA ratio and reduced levels of the eicosanoids, TXB2 and 6-keto-PGF1a, in their plasma compared with RO fish. Fish fed on FO and EO had a longer lasting and enduring response in their FA and eicosanoid concentrations, following a week of bacterial infection, compared with those fed on RO. EO, containing SDA and GLA and with a comparatively higher n3:n6 PUFA ratio, proved more effective than RO in compensating for immunity stress.

Item Details

Item Type:Refereed Article
Keywords:Eicosanoid,Fish oil,Infection,LC-PUFA,Stearidonic acid
Research Division:Agricultural and Veterinary Sciences
Research Group:Fisheries Sciences
Research Field:Aquaculture
Objective Division:Animal Production and Animal Primary Products
Objective Group:Fisheries - Aquaculture
Objective Field:Aquaculture Crustaceans (excl. Rock Lobster and Prawns)
Author:Bridle, AR (Dr Andrew Bridle)
Author:Carter, CG (Professor Chris Carter)
ID Code:84918
Year Published:2013
Web of Science® Times Cited:5
Deposited By:Sustainable Marine Research Collaboration
Deposited On:2013-06-06
Last Modified:2014-04-14
Downloads:0

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