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Occupational exposures and the development of new-onset asthma: a population-based cohort study from the ages of 13 to 44 years

Citation

Hoy, RF and Burgess, JA and Benke, G and Matheson, M and Morrison, S and Gurrin, L and Walters, EH and Dharmage, SC and Abramson, MJ, Occupational exposures and the development of new-onset asthma: a population-based cohort study from the ages of 13 to 44 years, Journal of Occupational and Environmental Medicine, 55, (3) pp. 235-239. ISSN 1076-2752 (2013) [Refereed Article]

Copyright Statement

Copyright 2013 Lippincott Williams and Wilkins

Official URL: http://www.acoem.org/JOEM.aspx

DOI: doi:10.1097/JOM.0b013e31827edefb

Abstract

Objective: To evaluate the risk of asthma associated with occupational exposures in a population-based cohort.

Methods: The risk of asthma was analyzed in 792 subjects who were asthma free at the age of 13 years. Occupational histories were obtained from subjects at the age of 44 years and occupational exposures determined with an asthma-specific job exposure matrix. Cumulative exposure to latex and risk of asthma was examined using Cox proportional hazards regression.

Results: Development of asthma was modestly related to exposure at any time to high molecular weight latex (odds ratio, 1.4; 95% confidence interval, 0.9-2.3). Cumulative latex exposure of 6 to 15 years was associated with a hazard ratio of 1.6 for the development of asthma and after 16 years increased to 2.65 (95% confidence interval, 1.28-5.47).

Conclusion: There is a significant association between cumulative occupational exposure to latex and new-onset asthma.

Item Details

Item Type:Refereed Article
Keywords:asthma
Research Division:Medical and Health Sciences
Research Group:Cardiorespiratory Medicine and Haematology
Research Field:Respiratory Diseases
Objective Division:Health
Objective Group:Clinical Health (Organs, Diseases and Abnormal Conditions)
Objective Field:Respiratory System and Diseases (incl. Asthma)
Author:Walters, EH (Professor Haydn Walters)
ID Code:84776
Year Published:2013
Web of Science® Times Cited:7
Deposited By:Medicine (Discipline)
Deposited On:2013-05-30
Last Modified:2014-05-07
Downloads:0

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