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On-line sample concentration via micelle to solvent stacking of cations prepared with aqueous organic solvents in capillary electrophoresis
Citation
Quirino, JP and Aranas, AT, On-line sample concentration via micelle to solvent stacking of cations prepared with aqueous organic solvents in capillary electrophoresis, Electrophoresis, 33, (14) pp. 2167-2175. ISSN 0173-0835 (2012) [Refereed Article]
Copyright Statement
Copyright 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
DOI: doi:10.1002/elps.201200023
Abstract
In this paper, by injecting a SDS micellar plug before the sample prepared in aqueous organic solvents, we show the on-line sample preconcentration of cations via micelle to solvent stacking (MSS) using solvents of as low as 30%. This extends the choice of stacking techniques to includemoderate amounts of organic solvent in the sample. The approach is akin to in-line solid phase extraction where the micellar plug acted as a transient micellar phase extractor. Basic studies were conducted (e.g. type and amount of organic solvent in the sample). The calculated sensitivity enhancement factors based on LOD obtained for the six test antipsychotic drugs were from 41 to 68. The peak signals were linear (R2 >0.99) from 0.2 to 10.0 µg/mL. The intraday and interday reproducibility (n = 10) for migration time, peak height, and corrected peak area were from 0.2 to 13.6%. The technique was also tested on spiked wastewater sample with minimal sample treatment (i.e. dilution and centrifugation).
Item Details
Item Type: | Refereed Article |
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Keywords: | antipsychotic drugs, capillary electrophoresis, micelle to solvent stacking, on-line sample concentration, organic solvent |
Research Division: | Chemical Sciences |
Research Group: | Analytical Chemistry |
Research Field: | Separation Science |
Objective Division: | Expanding Knowledge |
Objective Group: | Expanding Knowledge |
Objective Field: | Expanding Knowledge in the Chemical Sciences |
UTAS Author: | Quirino, JP (Associate Professor Lito Quirino) |
UTAS Author: | Aranas, AT (Miss T Aranas) |
ID Code: | 83359 |
Year Published: | 2012 |
Web of Science® Times Cited: | 17 |
Deposited By: | Austn Centre for Research in Separation Science |
Deposited On: | 2013-03-12 |
Last Modified: | 2017-11-01 |
Downloads: | 0 |
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