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Tramadol and seizures: An overview


Nichols, LJ, Tramadol and seizures: An overview, Australasian Journal of Neuroscience, 21, (1) pp. 1-7. ISSN 1032-335X (2011) [Refereed Article]

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Copyright 2011 ANNA (The Australasian Neuroscience Nurses Association)

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This review aims to expose the myths and misinterpretations of data concerning the risks of Tramadol Hydrochloride (Tramadol) and seizures within the neurosurgical environment. Within the neurosurgical environment there are differing views on the safety of Tramadol and the risk of seizures. Since Tramadolís release in Australia its unique biochemistry, pharmacodynamics and pharmacokinetics have resulted in it being one of the most widely prescribed analgesics and it continues to play an important role for neurosurgical patients. The non-controlled status and varied available routes of Tramadol administration also contribute to it being one of the most valued and widely prescribed analgesics. However the potential for seizures should not be underestimated, even when prescribed within the therapeutic range. Tramadol should be used cautiously and the benefits of treatment should outweigh the potential of seizures in patients who are at risk or taking other medications that lower the threshold for seizures. The phenomenon of seizures associated with Tramadol is likely to increase with increasing rates of analgesic and antidepressant use in the general population. Here lies two areas of importance for neuroscience nurses; managing patients admitted following seizures associated with Tramadol, and Tramadol administration to at risk patientís. It is crucial that nurses have a comprehensive knowledge of the seizure risk of Tramadol.

Item Details

Item Type:Refereed Article
Keywords:Tramadol, Seizures, convulsions, idiopathic, serotonin, neurosurgical
Research Division:Health Sciences
Research Group:Nursing
Research Field:Acute care
Objective Division:Health
Objective Group:Clinical health
Objective Field:Clinical health not elsewhere classified
UTAS Author:Nichols, LJ (Mrs Linda Nichols)
ID Code:82643
Year Published:2011
Deposited By:Health Sciences B
Deposited On:2013-02-08
Last Modified:2013-06-26
Downloads:7 View Download Statistics

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