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Modelling damaged lung pressure–volume behaviour

Citation

Gerard, CS and Gale, TJ and Dargaville, PA, Modelling damaged lung pressure-volume behaviour, Proceedings of the 5th Biomedical Engineering International Conference, 5-7 December, UbonRatchathani, Thailand, pp. 1-5. ISBN 978-1-4673-4892-8 (2012) [Refereed Conference Paper]

Copyright Statement

Copyright 2012 IEEE

DOI: doi:10.1109/BMEiCon.2012.6465419

Abstract

This paper investigates the performance of a model of time dependent lung pressure-volume behaviour when applied to experimental data from neonatal piglets. The model was built using Labview and applied to experimental dynamic recruitment data from the previously published studies of other researchers. The experimental data featured multiple tidal pressure-volume loops during inflation and deflation to/from total lung capacity (TLC) respectively, but the model was not able to replicate these satisfactorily. Model performance was substantially poorer during deflation from TLC (deflation limb) than during inflation to TLC (Inflation limb). Ideas are discussed for improving the model.

Item Details

Item Type:Refereed Conference Paper
Keywords:Bates & Irvin lung model, saline lavage, time dependence, recruitment, half inflation pressure, critical pressure, labview, lung unit, asymptotic volume, neonatal piglets
Research Division:Engineering
Research Group:Biomedical Engineering
Research Field:Biomedical Engineering not elsewhere classified
Objective Division:Health
Objective Group:Clinical Health (Organs, Diseases and Abnormal Conditions)
Objective Field:Respiratory System and Diseases (incl. Asthma)
Author:Gerard, CS (Mr Calverly Gerard)
Author:Gale, TJ (Dr Timothy Gale)
Author:Dargaville, PA (Professor Peter Dargaville)
ID Code:82439
Year Published:2012
Deposited By:Engineering
Deposited On:2013-02-01
Last Modified:2014-08-13
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