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The relationship between antioxidant supplements and oxidative stress in renal transplant recipients; a review
journal contribution
posted on 2023-05-22, 23:38 authored by Melanie BlackhallMelanie Blackhall, Coombes, JS, Fassett, RGRenal transplant recipients (RTRs) have elevated oxidative stress and a high incidence of cardiovascular morbidity and mortality. Although recent studies do not support the use of antioxidant supplements as a cardioprotectant in the general population, evidence suggests that RTRs may represent individuals that would benefit from this therapy. RTRs have elevated oxidative stress probably caused by the immunosuppressive therapy, and although only a small number of studies have examined the effects of antioxidant supplementation in these patients, most have reported beneficial findings. This review discusses these studies along with the rationale for the use of antioxidant supplements in RTRs and a call for more research to investigate this important topic.
History
Publication title
ASAIO JournalVolume
50Issue
5Pagination
451-457ISSN
1058-2916Department/School
Tasmanian School of MedicinePublisher
Lippincott Williams & WilkinsPlace of publication
530 Walnut St, Philadelphia, USA, Pa, 19106-3621Repository Status
- Restricted