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The relationship between antioxidant supplements and oxidative stress in renal transplant recipients; a review

Citation

Blackhall, ML and Coombes, J and Fassett, RG, The relationship between antioxidant supplements and oxidative stress in renal transplant recipients; a review, ASAIO Journal, 50, (5) pp. 451-457. ISSN 1058-2916 (2004) [Substantial Review]

Abstract

Renal transplant recipients (RTRs) have elevated oxidative stress and a high incidence of cardiovascular morbidity and mortality. Although recent studies do not support the use of antioxidant supplements as a cardioprotectant in the general population, evidence suggests that RTRs may represent individuals that would benefit from this therapy. RTRs have elevated oxidative stress probably caused by the immunosuppressive therapy, and although only a small number of studies have examined the effects of antioxidant supplementation in these patients, most have reported beneficial findings. This review discusses these studies along with the rationale for the use of antioxidant supplements in RTRs and a call for more research to investigate this important topic.

Item Details

Item Type:Substantial Review
Research Division:Medical and Health Sciences
Research Group:Clinical Sciences
Research Field:Nephrology and Urology
Objective Division:Health
Objective Group:Clinical Health (Organs, Diseases and Abnormal Conditions)
Objective Field:Clinical Health (Organs, Diseases and Abnormal Conditions) not elsewhere classified
Author:Blackhall, ML (Mrs Melanie Blackhall)
Author:Coombes, J (Associate Professor Jeff Coombes)
Author:Fassett, RG (Professor Robert Fassett)
ID Code:81279
Year Published:2004
Deposited By:Medicine (Discipline)
Deposited On:2012-11-28
Last Modified:2012-11-28
Downloads:0

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