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Production of novel polymer monolithic columns, with stationary phase gradients, using cyclic olefin co-polymer (COC) optical filters

Citation

Currivan, S and Connolly, D and Paull, B, Production of novel polymer monolithic columns, with stationary phase gradients, using cyclic olefin co-polymer (COC) optical filters, Analyst, 137, (11) pp. 2559-2566. ISSN 0003-2654 (2012) [Refereed Article]

Copyright Statement

Copyright 2012 The Royal Society of Chemistry

DOI: doi:10.1039/c2an35316d

Abstract

Polymer monolithic columns with controlled surface ligand density, providing stationary phase gradients within monolithic capillary columns, have been developed using photo-grafting through optical filters. Utilising commercially available cyclic olefin co-polymer (COC) films, the production of an optical filter capable of attenuating UV irradiation, in a tailored manner, was investigated. This novel optical filter was successfully applied to the surface modification of poly(BuMA-co-EDMA) monolithic columns in a multi-step grafting procedure. Fabricated columns were subjected to scanning capacitively coupled contactless conductivity (sC4D), to determine the distribution of the grafted functional groups, axially along the column. Further modification to produce a chelating stationary phase gradient of iminodiacetic acid (IDA) was demonstrated. To demonstrate the distribution of the IDA sites, a metal cation (Cu2+) was complexed to the IDA forming a chelate. Upon the formation of a complex of IDA with Cu2+, an overall drop in conductive response was observed. The COC optical filter was also used in the fabrication of a grafted gradient of strong cation exchanger (SCX), sulphopropyl methacrylate (SPM) upon a polymer monolith, demonstrating the broader applicability of such a filter.

Item Details

Item Type:Refereed Article
Research Division:Chemical Sciences
Research Group:Analytical Chemistry
Research Field:Separation Science
Objective Division:Expanding Knowledge
Objective Group:Expanding Knowledge
Objective Field:Expanding Knowledge in the Chemical Sciences
Author:Currivan, S (Dr Sinead Currivan)
Author:Paull, B (Professor Brett Paull)
ID Code:81028
Year Published:2012
Web of Science® Times Cited:7
Deposited By:Austn Centre for Research in Separation Science
Deposited On:2012-11-21
Last Modified:2015-11-17
Downloads:0

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