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Chemical restraint of Southern Elephant Seals Mirounga leonina: Use of medetomidine, ketamine and atipamezole and comparison with other cyclohexamine-based combinations

Citation

Woods, R and McLean, SR and Nicol, SC and Burton, HR, Chemical restraint of Southern Elephant Seals Mirounga leonina: Use of medetomidine, ketamine and atipamezole and comparison with other cyclohexamine-based combinations, British Veterinary Journal, 152, (2) pp. 213-224. ISSN 0007-1935 (1996) [Refereed Article]


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DOI: doi:10.1016/S0007-1935(96)80075-3

Abstract

A study was conducted to assess the effectiveness of the -2 agonist medetoinidine for sedation of pre-moulting, mature female southern elephant seals (Mirounga leonina). Two animals were sedated with a single intramuscular dose of medetomidine (0.013 and 0.027 mg kg−1). A further two groups of five animals received medetomidine (0.017 mg kg−1) combined with ketamine (1.90 mg kg−1) and, 20 min later, either saline or the -2 antagonist atipamezole (0.04 mg kg−1) intravenously. Medetomidine alone did not give sufficient restraint to permit intravenous access. The response appeared to be similar to previous findings with ketamine and xylazine. Administration of atipamezole had little effect upon the level and time-course of restraint. Ketamine and medetomidine seem to offer few advantages over ketamine and xylazine or other cyclohexamine-drug combinations for routine chemical restraint of southern elephant seals.

Item Details

Item Type:Refereed Article
Keywords:Southern elephant seal; chemical restraint; medetomidine; ketamine; -2 adrenergic agonist
Research Division:Agricultural and Veterinary Sciences
Research Group:Veterinary Sciences
Research Field:Veterinary Pharmacology
Objective Division:Expanding Knowledge
Objective Group:Expanding Knowledge
Objective Field:Expanding Knowledge in the Environmental Sciences
Author:Woods, R (Dr Rupert Woods)
Author:McLean, SR (Professor Stuart McLean)
Author:Nicol, SC (Associate Professor Stewart Nicol)
ID Code:7939
Year Published:1996
Web of Science® Times Cited:6
Deposited By:Anatomy and Physiology
Deposited On:1996-08-01
Last Modified:2011-08-19
Downloads:0

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