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Statistical analysis of fiber area in human skeletal muscle

Citation

McGuigan, MR and Kraemer, WJ and Deschenes, MR and Gordon, SE and Kitaura, T and Scheett, TP and Sharman, MJ and Staron, RS, Statistical analysis of fiber area in human skeletal muscle, Canadian Journal of Applied Physiology, 2002 Aug, (27(4)) pp. 415-22. ISSN 1066-7814 (2002) [Refereed Article]

Abstract

Previous research has indicated that 50 fiber measurements per individual for type I and II fibers would be sufficient to characterize the fiber areas. This study replicated the work of McCall et al. (1998) using the three major fiber types (I, IIA, and IIB) and sampling larger populations of fibers. Random blocks of fibers were also examined to investigate how well they correlated with the overall mean average fiber area. Using random blocks of 50 fibers provided an accurate reflection of the type IIB fibers (r = 0.96-0.98) but not for the type I (r = 0.85-0.94) or IIA fibers (r = 0.80-0.91). Type I fibers were consistently reflected by a random block of 150 fibers (r = 0.95-0.98) while type IIA fibers required random blocks of 200 fibers (r = 0.94-0.98), which appeared to provide an accurate reflection of the cross-sectional area. These results indicate that for a needle biopsy different numbers of fibers are needed depending on the fiber type to accurately characterize the mean fiber population.

Item Details

Item Type:Refereed Article
Research Division:Medical and Health Sciences
Research Group:Human Movement and Sports Science
Research Field:Exercise Physiology
Objective Division:Health
Objective Group:Health and Support Services
Objective Field:Health and Support Services not elsewhere classified
Author:Sharman, MJ (Dr Matt Sharman)
ID Code:79137
Year Published:2002
Deposited By:Health Sciences A
Deposited On:2012-08-20
Last Modified:2012-08-20
Downloads:0

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