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Effect of explosive resistance training on titin and myosin heavy chain isoforms in trained subjects


McGuigan, MR and Sharman, MJ and Newton, RU and Davie, AJ and Murphy, AJ and McBride, JM, Effect of explosive resistance training on titin and myosin heavy chain isoforms in trained subjects, Journal of Strength and Conditioning Research: The Research Journal of The National Strength and Conditioning Association, 2003 Nov, (17(4)) pp. 645-51. ISSN 1064-8011 (2003) [Refereed Article]


The purpose of this investigation was to evaluate changes in myosin heavy chain (MyHC) and titin isoforms after using various loads during explosive jump squat training. Twenty-four male athletic subjects were recruited for this study. Two experimental groups performed 8-weeks of jump squats using either 30% (n = 9) or 80% (n = 9) of their previously determined 1 repetition maximum. A third group served as controls (n = 6). Muscle biopsies were obtained before and after 8 weeks from vastus lateralis. The analysis of titin within these subjects confirmed that human skeletal muscle contains 2 isoforms of titin. There was no significant group x time interaction for MyHC or titin isoform expression. The data from this investigation indicates that a relatively short period of explosive resistance training results in negligible changes in the expression of MyHC or titin isoforms.

Item Details

Item Type:Refereed Article
Research Division:Health Sciences
Research Group:Sports science and exercise
Research Field:Exercise physiology
Objective Division:Health
Objective Group:Evaluation of health and support services
Objective Field:Evaluation of health and support services not elsewhere classified
UTAS Author:Sharman, MJ (Dr Matt Sharman)
ID Code:79077
Year Published:2003
Deposited By:Health Sciences A
Deposited On:2012-08-15
Last Modified:2012-08-15

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