Austrocolorone B and austrocolorin B1, cytotoxic anthracenone dimers from the Tasmanian mushroom Cortinarius vinosipes Gasparini

The yellow dihydroanthracenone dimer, austrocolorin B₁ and the unique violet-red 1,4-anthraquinone dimer, austrocolorone B, were isolated from the Tasmanian mushroom Cortinarius vinosipes and their structures and stereochemistry were determined from spectroscopic data. Austrocolorin B₁ and austrocolorone B were found to exhibit potent cytotoxic activity in vitro against the murine lymphoblast (P388D₁) cell line with IC₅₀ values in the range 10–31 μg/mL.