eCite Digital Repository

Austrocolorone B and austrocolorin B1, cytotoxic anthracenone dimers from the Tasmanian mushroom Cortinarius vinosipes Gasparini

Citation

Beattie, KD and Thompson, DR and Tiralongo, E and Ratkowsky, D and May, TW and Gill, M, Austrocolorone B and austrocolorin B1, cytotoxic anthracenone dimers from the Tasmanian mushroom Cortinarius vinosipes Gasparini, Tetrahedron Letters, 52, (42) pp. 5448-5451. ISSN 0040-4039 (2011) [Refereed Article]


Preview
PDF
Restricted - Request a copy
437Kb
  

Copyright Statement

Copyright 2011 Elsevier Ltd.

DOI: doi:10.1016/j.tetlet.2011.08.015

Abstract

The yellow dihydroanthracenone dimer, austrocolorin B1 and the unique violet-red 1,4-anthraquinone dimer, austrocolorone B, were isolated from the Tasmanian mushroom Cortinarius vinosipes and their structures and stereochemistry were determined from spectroscopic data. Austrocolorin B1 and austrocolorone B were found to exhibit potent cytotoxic activity in vitro against the murine lymphoblast (P388D1) cell line with IC50 values in the range 10–31 μg/mL.

Item Details

Item Type:Refereed Article
Keywords:cytotoxic, anthraquinone, tricolorin, Australian fungi
Research Division:Biological Sciences
Research Group:Biochemistry and Cell Biology
Research Field:Biochemistry and Cell Biology not elsewhere classified
Objective Division:Environment
Objective Group:Flora, Fauna and Biodiversity
Objective Field:Forest and Woodlands Flora, Fauna and Biodiversity
Author:Ratkowsky, D (Dr David Ratkowsky)
ID Code:78321
Year Published:2011
Deposited By:Plant Science
Deposited On:2012-06-21
Last Modified:2017-08-23
Downloads:0

Repository Staff Only: item control page