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New strategies in neuroprotection and neurorepair


Antonelli, MC and Guillemin, GJ and Raisman-Vozari, R and Del-Bel, EA and Aschner, M and Collins, MA and Tizabi, Y and Moratalla, R and West, AK, New strategies in neuroprotection and neurorepair, Neurotoxicity Research, 21, (1) pp. 49-56. ISSN 1029-8428 (2012) [Refereed Article]

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Copyright 2011 Springer Science+Business Media, LLC

DOI: doi:10.1007/s12640-011-9265-8


There are currently few clinical strategies in place, which provide effective neuroprotection and repair, despite an intense international effort over the past decades. One possible explanation for this is that a deeper understanding is required of how endogenous mechanisms act to confer neuroprotection. This mini-review reports the proceedings of a recent workshop "Neuroprotection and Neurorepair: New Strategies" (Iguazu Falls, Misiones, Argentina, April 11-13, 2011, Satellite Symposium of the V Neurotoxicity Society Meeting, 2011) in which four areas of active research were identified to have the potential to generate new insights into this field. Topics discussed were (i) metallothionein and other multipotent neuroprotective molecules; (ii) oxidative stress and their signal mediated pathways in neuroregeneration; (iii) neurotoxins in glial cells, and (iv) drugs of abuse with neuroprotective effects.

Item Details

Item Type:Refereed Article
Keywords:neuroprotection, oxidative stress, metallothionein, glia, cannabinoids, alcohol
Research Division:Biomedical and Clinical Sciences
Research Group:Neurosciences
Research Field:Central nervous system
Objective Division:Health
Objective Group:Clinical health
Objective Field:Clinical health not elsewhere classified
UTAS Author:West, AK (Professor Adrian West)
ID Code:77577
Year Published:2012
Web of Science® Times Cited:13
Deposited By:Menzies Institute for Medical Research
Deposited On:2012-05-04
Last Modified:2017-11-06

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