Laitinen, TT and Pahkala, K and Magnussen, CG and Viikari, JSA and Oikonen, M and Taittonen, L and Mikkila, V and Jokinen, E and Hutri-Kahonen, N and Laitinen, T and Kahonen, M and Lehtimaki, T and Raitakari, OT and Juonala, M, Ideal Cardiovascular Health in Childhood and Cardiometabolic Outcomes in Adulthood: The Cardiovascular Risk in Young Finns Study, Circulation, 125, (16) pp. 1971-1978. ISSN 0009-7322 (2012) [Refereed Article]
Copyright 2012 American Heart Association, Inc.
Background: The American Heart Association (AHA) defined a new concept, cardiovascular health, and determined metrics needed to monitor it over time as part of its 2020 Impact Goal definition. Ideal cardiovascular health is defined by the presence of both ideal health behaviors and ideal health factors. The applicability of this concept to a cohort of children and its relationship with cardiometabolic outcomes in adulthood has not been reported.
Methods and Results: The sample comprised 856 participants aged 12 to 18 years (mean age 15.0 years) from the Cardiovascular Risk in Young Finns Study cohort. Participants were followed up for 21 years since baseline (1986) and had data available concerning health factors and behaviors in childhood and cardiometabolic outcomes in adulthood (2007). The number of ideal cardiovascular health metrics present in childhood was associated with reduced risk of hypertension (odds ratio [95% confidence interval] 0.66 [0.52– 0.85], P < 0.001), metabolic syndrome (0.66 [0.52– 0.77], P < 0.001), high low-density lipoprotein cholesterol (0.66 [0.52– 0.85], P = 0.001), and high-risk carotid artery intima-media thickness (0.75 [0.60–0.94], P = 0.01) in adulthood. All analyses were age and sex adjusted, and the results were not altered after additional adjustment with socioeconomic status.
Conclusions: The number of ideal cardiovascular health metrics present in childhood predicts subsequent cardiometabolic health in adulthood. Our findings suggest that pursuit of ideal cardiovascular health in childhood is important to prevent cardiometabolic outcomes in adulthood.
|Item Type:||Refereed Article|
|Keywords:||cardiovascular diseases, epidemiology, risk factors, children|
|Research Division:||Medical and Health Sciences|
|Research Group:||Public Health and Health Services|
|Objective Group:||Clinical Health (Organs, Diseases and Abnormal Conditions)|
|Objective Field:||Cardiovascular System and Diseases|
|Author:||Magnussen, CG (Dr Costan Magnussen)|
|Web of Science® Times Cited:||111|
|Deposited By:||Menzies Institute for Medical Research|
Repository Staff Only: item control page