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Centrifugally-driven sample extraction, preconcentration and purification in microfluidic compact discs
Citation
Vazquez, M and Brabazon, D and Shang, F and Omamogho, JO and Glennon, JD and Paull, B, Centrifugally-driven sample extraction, preconcentration and purification in microfluidic compact discs, Trends in Analytical Chemistry, 30, (10) pp. 1575-1586. ISSN 0165-9936 (2011) [Refereed Article]
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The definitive version is available at http://www.sciencedirect.com
DOI: doi:10.1016/j.trac.2011.07.007
Abstract
Centrifugally-driven microfluidic compact discs (l-CDs) have attracted significant interest within the analytical science community in the past decade, with the primary focus on the potential of such platforms for performing parallel and/or multiplex biological assays and further application in biomedical diagnostics. More recently, l-CD-based devices were also applied to environmental analysis as platforms for multi-sample extraction and transportation, prior to off-disc analysis in the laboratory.
This review critically summarizes recent developments in l-CD platforms for sample extraction, preconcentration, fractionation and purification in bioanalytical and environmental applications. We also summarize the common methods employed in the fabrication of l-CD platforms. Further, we discuss preparation of stationary phases in microfluidic channels embedded in l-CDs,
as applications of l-CDs in sample extraction are generally based on enclosed series of extraction phases and microcolumns.
Item Details
Item Type: | Refereed Article |
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Keywords: | Centrifugally-driven microextraction, Electrophoretic separation, Fractionation, Lab-on-a-disc, Microfluidic compact disc (l-CD), Monolithic stationary phase, Packed stationary phase, Preconcentration, Purification, Sample extraction |
Research Division: | Chemical Sciences |
Research Group: | Analytical chemistry |
Research Field: | Separation science |
Objective Division: | Expanding Knowledge |
Objective Group: | Expanding knowledge |
Objective Field: | Expanding knowledge in the mathematical sciences |
UTAS Author: | Paull, B (Professor Brett Paull) |
ID Code: | 76747 |
Year Published: | 2011 |
Web of Science® Times Cited: | 23 |
Deposited By: | Chemistry |
Deposited On: | 2012-03-13 |
Last Modified: | 2012-05-11 |
Downloads: | 9 View Download Statistics |
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