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Mendel's Genes: Toward a Full Molecular Characterization
Citation
Reid, JB and Ross, JJ, Mendel's Genes: Toward a Full Molecular Characterization, Genetics: A Periodical Record of Investigations Bearing on Heredity and Variation, 189, (1) pp. 3-10. ISSN 1943-2631 (2011) [Refereed Article]
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Copyright Statement
Copyright 2011 Genetics Society of America
DOI: doi:10.1534/genetics.111.132118
Abstract
The discipline of classical genetics is founded on the hereditary behavior of the seven genes studied by Gregor Mendel. The
advent of molecular techniques has unveiled much about the identity of these genes. To date, four genes have been sequenced: A
(flower color), LE (stem length), I (cotyledon color), and R (seed shape). Two of the other three genes, GP (pod color) and FA (fasciation),
are amenable to candidate gene approaches on the basis of their function, linkage relationships, and synteny between the pea and
Medicago genomes. However, even the gene (locus) identity is not known for certain for the seventh character, the pod form,
although it is probably V. While the nature of the mutations used by Mendel cannot be determined with certainty, on the basis of
the varieties available in Europe in the 1850s, we can speculate on their nature. It turns out that these mutations are attributable to
a range of causes—from simple base substitutions and changes to splice sites to the insertion of a transposon-like element. These
findings provide a fascinating connection between Mendelian genetics and molecular biology that can be used very effectively in
teaching new generations of geneticists. Mendel’s characters also provide novel insights into the nature of the genes responsible for
characteristics of agronomic and consumer importance.
Item Details
Item Type: | Refereed Article |
---|---|
Research Division: | Biological Sciences |
Research Group: | Plant biology |
Research Field: | Plant physiology |
Objective Division: | Plant Production and Plant Primary Products |
Objective Group: | Horticultural crops |
Objective Field: | Horticultural crops not elsewhere classified |
UTAS Author: | Reid, JB (Professor Jim Reid) |
UTAS Author: | Ross, JJ (Associate Professor John Ross) |
ID Code: | 75863 |
Year Published: | 2011 |
Web of Science® Times Cited: | 23 |
Deposited By: | Plant Science |
Deposited On: | 2012-02-17 |
Last Modified: | 2017-11-15 |
Downloads: | 0 |
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