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Genetic eye research in Tasmania: a historical overview
Although considerable recent work on hereditary eye diseases in Tasmanian families has been published, much of this depended on a century of meticulous pedigree collection by earlier clinical researchers. This article reviews some of the historical papers and the importance they have played in gene discovery and understanding of ophthalmic genetics. Tasmanian families have contributed to the identification of genes for X-linked megalocornea, Leber’s hereditary optic neuropathy, retinitis pigmentosa, congenital cataract, ptosis, keratoconus, glaucoma and myopia. The true value of the Tasmanian pedigrees will be realized with the translation of genetic discoveries into early diag- nosis and treatment for these eye diseases.
History
Publication title
Clinical and Experimental OphthalmologyVolume
40Pagination
205-210ISSN
1442-9071Department/School
Tasmanian School of MedicinePublisher
Wiley-Blackwell PublishingPlace of publication
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The definitive published version is available online at: http://www3.interscience.wiley.com/Repository Status
- Restricted