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Quantitative urinary excretion of unmetabolised N tau-[Me-C-14]methylhistidine by the common ringtail possum (Pseudocheirus peregrinus) Marsupialia
Citation
Watson, S and Foley, W and McLean, S and Brandon, S and Davies, NW, Quantitative urinary excretion of unmetabolised N tau-[Me-C-14]methylhistidine by the common ringtail possum (Pseudocheirus peregrinus) Marsupialia, Comparative Biochemistry and Physiology. A: Physiology, 115, (1) pp. 53-55. ISSN 0300-9629 (1996) [Refereed Article]
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DOI: doi:10.1016/0300-9629(96)00001-1
Abstract
Six common ringtail possums (Psewbcheirus peregrinus) were intravenously injected with a standard dose of radioactive 3-Methylhistidine (N’-[Me-‘4C]MeH). The dose was rapidly and quantitatively excreted by the possums. More than 90% of radioactivity was recovered within 3 days. Thin layer chromatography and mass spectroscopy showed that 97% of recovered radioactivity was associated with unmetabolised N’-[Me-14C)MeH. These data satisfy two key requirements for the validity of urinary 3-Methylhistidine (Nr-3MeH) excretion as an index of muscle protein catabolism in P. peregrinus.
Item Details
Item Type: | Refereed Article |
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Keywords: | 3-Methylhistidine; Nô-[Me-14C]MeH; muscle protein catabolism; common ringtail possum; Pseudocheirus peregrinus; arboreal folivore; marsupial; eucalyptus |
Research Division: | Biomedical and Clinical Sciences |
Research Group: | Pharmacology and pharmaceutical sciences |
Research Field: | Basic pharmacology |
Objective Division: | Environmental Management |
Objective Group: | Other environmental management |
Objective Field: | Other environmental management not elsewhere classified |
UTAS Author: | McLean, S (Professor Stuart McLean) |
UTAS Author: | Brandon, S (Mrs Susan Brandon) |
UTAS Author: | Davies, NW (Associate Professor Noel Davies) |
ID Code: | 7508 |
Year Published: | 1996 |
Web of Science® Times Cited: | 2 |
Deposited By: | Pharmacy |
Deposited On: | 1996-08-01 |
Last Modified: | 2011-08-19 |
Downloads: | 0 |
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