University of Tasmania
Browse

File(s) under permanent embargo

Pilot Study of Nebulised Morphine for Dyspnoea in Palliative Care Patients

journal contribution
posted on 2023-05-21, 17:34 authored by Gregory PetersonGregory Peterson, Young, R, Dunne, P, Galloway, G, Parks, T
Objective: To investigate the efficacy of nebulised morphine for dyspnoea in a controlled trial involving eight terminally ill patients. Method: Over three consecutive days, patients received treatment for one day with four nebulised doses of either sodium chloride 0.9%, morphine 2.5 mg or morphine 5 mg. Both subjective severity of dyspnoea and respiratory function were monitored with each treatment. Results: Analysis of variance indicated that there was a statistically significant difference in the subjective symptoms of dyspnoea and respiratory function between individual patients. However, there was no evidence of any beneficial effects of nebulised morphine or saline in these patients, who were all receiving regular morphine by either the oral or subcutaneous route. Conclusion: This small trial suggests that there would be limited value in adding nebulised morphine, at the dosage studied, to oral or subcutaneous therapy in palliative care patients with dyspnoea.

History

Publication title

Australian Journal of Hospital Pharmacy

Volume

26

Issue

5

Pagination

545-547

ISSN

0310-6810

Department/School

School of Pharmacy and Pharmacology

Publisher

Society of Hospital Pharmacists of Australia

Place of publication

Australia

Rights statement

Copyrights 1999 Society of Hospital Pharmacists of Australia

Repository Status

  • Restricted

Socio-economic Objectives

Other health not elsewhere classified

Usage metrics

    University Of Tasmania

    Exports

    RefWorks
    BibTeX
    Ref. manager
    Endnote
    DataCite
    NLM
    DC