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A critical review of pharmacoeconomic studies of acamprosate


Poldrugo, F and Haeger, DA and Comte, S and Walburg, J and Palmer, AJ, A critical review of pharmacoeconomic studies of acamprosate, Alcohol and Alcoholism, 40, (5) pp. 422-430. ISSN 0735-0414 (2005) [Refereed Article]

DOI: doi:10.1093/alcalc/agh171


Aims: This review assessed the published data on the cost-effectiveness of acamprosate for the treatment of alcohol dependence. Methods: Four Markov modelling studies have assessed the therapeutic benefit and economic impact of acamprosate on the treatment of alcohol dependence. These have evaluated both short-term and long-term outcomes and have used German, Belgian, and Spanish costings. A fifth prospective cohort study collected real outcomes and data on expenditure during a 1 year study follow-up period. Results: All five studies have produced consistent results, showing the use of acamprosate, which enhances abstinence rates, to reduce the total costs of treatment and thus be dominant over other rehabilitation strategies not involving pharmacotherapy. In all of the studies, the principal cost-driver is hospitalization. Although there is a short-term increase in treatment costs associated with drug acquisition, these are recovered from long-term savings attributable to reduced hospitalization and rehabilitation costs. © The Author 2005. Published by Oxford University Press on behalf of the Medical Council on Alcohol. All rights reserved.

Item Details

Item Type:Refereed Article
Research Division:Economics
Research Group:Applied economics
Research Field:Health economics
Objective Division:Health
Objective Group:Evaluation of health and support services
Objective Field:Evaluation of health and support services not elsewhere classified
UTAS Author:Palmer, AJ (Professor Andrew Palmer)
ID Code:74686
Year Published:2005
Web of Science® Times Cited:11
Deposited By:Research Division
Deposited On:2011-12-12
Last Modified:2011-12-13

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