The prevalence of co-morbid depression in adults with Type 1 diabetes: systematic literature review
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Barnard, KD and Skinner, TC and Peveler, R, The prevalence of co-morbid depression in adults with Type 1 diabetes: systematic literature review, Diabetic Medicine, 23, (4) pp. 445-448 . ISSN 0742-3071 (2006) [Refereed Article]
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Aim: To review the literature estimating the cross-sectional prevalence of clinical depression in adults with Type 1 diabetes. Methods: Electronic databases and published references were used to identify studies published between January 2000 and June 2004, with a previous meta-analysis used to identify studies before 1 January 2000. Results: Between January 2000 and June 2004, a further five eligible studies were identified. Only one was a controlled study using diagnostic interviewing to determine rates of depression. Taking all of the eligible studies identified by the previous meta-analysis and this search, the prevalence of clinical depression in controlled studies was 12.0% for people with diabetes compared with 3.2% for control subjects. In studies with no control group, the prevalence of clinical depression was 13.4%. Conclusion: There are wide-ranging differences reported in the various studies on the prevalence of depression in Type 1 diabetes. In view of the differing methods of diagnosis and small participant numbers, the results should be viewed with caution. A controlled study using diagnostic interviewing techniques to determine levels of depression is recommended to provide a clearer picture of both the prevalence and characteristics of that depression. © 2006 Diabetes UK.
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