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Tracking of Serum Lipid Levels, Blood Pressure, and Body Mass Index from Childhood to Adulthood: The Cardiovascular Risk in Young Finns Study

Citation

Juhola, J and Magnussen, CG and Viikari, JSA and Kahonen, M and Hutri-Kahonen, N and Jula, A and Lehtimaki, T and Akerblom, HK and Pietikainen, M and Laitinen, T and Jokinen, E and Taittonen, L and Raitakari, OT and Juonala, M, Tracking of Serum Lipid Levels, Blood Pressure, and Body Mass Index from Childhood to Adulthood: The Cardiovascular Risk in Young Finns Study, Journal of Pediatrics, 159, (4) pp. 584-590. ISSN 0022-3476 (2011) [Refereed Article]


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Copyright Statement

Copyright 2011 Mosby

DOI: doi:10.1016/j.jpeds.2011.03.021

Abstract

Objectives To examine tracking and predictiveness of childhood lipid levels, blood pressure, and body mass index for risk profile in adulthood and the best age to measure the childhood risk factor levels. Study design Study subjects were participants of the longitudinal Cardiovascular Risk in Young Finns Study, started in 1980 (age 3, 6, 9, 12, 15, and 18 years). A total of 2204 subjects participated to the 27-year follow-up in 2007 (age, 30 to 45 years). Results In both sex groups and in all age groups, childhood risk factors were significantly correlated with levels in adulthood. The correlation coefficients for cholesterol levels and body mass index were 0.43 to 0.56 (P < .0001), and for blood pressure and triglyceride levels, they were 0.21 to 0.32 (P < .0001). To recognize children with abnormal adult levels, the National Cholesterol Education Program and the National High Blood Pressure Education Program cutoff points for lipid and blood pressure values and international cutoff points for overweight and obesity were used. Age seemed to affect associations. The best sensitivity and specificity rates were observed in 12- to 18-year-old subjects. Conclusions Childhood blood pressure, serum lipid levels, and body mass index correlate strongly with values measured in middle age. These associations seemed to be stronger with increased age at measurements.

Item Details

Item Type:Refereed Article
Research Division:Medical and Health Sciences
Research Group:Cardiorespiratory Medicine and Haematology
Research Field:Cardiology (incl. Cardiovascular Diseases)
Objective Division:Health
Objective Group:Clinical Health (Organs, Diseases and Abnormal Conditions)
Objective Field:Cardiovascular System and Diseases
Author:Magnussen, CG (Dr Costan Magnussen)
ID Code:73204
Year Published:2011
Web of Science® Times Cited:147
Deposited By:Menzies Institute for Medical Research
Deposited On:2011-09-21
Last Modified:2017-11-07
Downloads:9 View Download Statistics

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