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Age-related differences in corticospinal excitability during a Go/NoGo task
Citation
Fujiyama, H and Tandonnet, C and Summers, JJ, Age-related differences in corticospinal excitability during a Go/NoGo task, Psychophysiology, 48, (10) pp. 1448-1455. ISSN 0048-5772 (2011) [Refereed Article]
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Copyright Statement
Copyright © 2011 Society for Psychophysiological Research The definitive published version is available online at: http://www.interscience.wiley.com
DOI: doi:10.1111/j.1469-8986.2011.01201.x
Abstract
Age-related slowing of reaction times (RTs) is well documented but whether the phenomenon reflects deficits in
movement preparation and/or response generation processes is unclear. To gain further insight into this issue, transcranial
magnetic stimulation (TMS) was used to investigate motor cortex (M1) excitability and short-interval intracortical
inhibitory (SICI) processes during a Go/NoGo RTtask in younger and older adults. Single- and paired-pulse
TMS was delivered over the left M1 during preparation and response generation periods in a right-hand muscle.
Younger adults had shorter RTs and a larger increase in corticospinal excitability at response generation period than
older adults. SICI modulation for both groups showed a large reduction in inhibition immediately prior to EMGonset.
These findings indicate age-related differences in corticospinal excitability during the response generation stage of
sensorimotor information processing.
Item Details
Item Type: | Refereed Article |
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Keywords: | Aging, Go/NoGo reaction time, Corticospinal excitability, Intracortical inhibition, Transcranial magnetic |
Research Division: | Psychology |
Research Group: | Cognitive and computational psychology |
Research Field: | Sensory processes, perception and performance |
Objective Division: | Expanding Knowledge |
Objective Group: | Expanding knowledge |
Objective Field: | Expanding knowledge in psychology |
UTAS Author: | Fujiyama, H (Dr Hakuei Fujiyama) |
UTAS Author: | Tandonnet, C (Dr Christophe Tandonnet) |
UTAS Author: | Summers, JJ (Professor Jeffery Summers) |
ID Code: | 73165 |
Year Published: | 2011 |
Web of Science® Times Cited: | 25 |
Deposited By: | Psychology |
Deposited On: | 2011-09-16 |
Last Modified: | 2014-12-05 |
Downloads: | 0 |
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