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Factors associated with quality of life in 7-year survivors of stroke

Citation

Leach, MJ and Gall, SL and Dewey, HM and Macdonell, RAL and Thrift, AG, Factors associated with quality of life in 7-year survivors of stroke, Journal of Neurology, Neurosurgery and Psychiatry, 82, (12) pp. 1365-1371. ISSN 0022-3050 (2011) [Refereed Article]


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Copyright Statement

Copyright © 2011 BMJ Publishing

DOI: doi:10.1136/jnnp.2010.234765

Abstract

Background Little is known about health-related quality of life (HRQoL) in the long term after stroke. Aim The aim of this study was to assess the level of, and factors associated with, HRQoL at 7 years post-stroke. Methods All stroke cases from a prospective community-based stroke incidence study (excluding subarachnoid haemorrhage) were assessed 7 years after stroke. HRQoL was measured with the Assessment of Quality of Life instrument. Proportional odds ordinal logistic regression was used to determine factors associated with HRQoL at 7 years post-stroke. Results Overall, 1321 stroke cases were recruited. Seven years after stroke, 413 (31.2%) were alive and 328 (79.4%) were assessed. Those assessed were less often current smokers pre-stroke than those not assessed (p<0.01). Seventy-six survivors (23%) had very poor HRQoL (range: 0.038 to 0.100). Factors present at 7 years that were associated with better 7-year HRQoL were independence in instrumental activities of daily living (IADL) (estimated OR¼11.2, 95% CI 4.87 to 25.6, p<0.001), independence in basic activities of daily living (BADL) (OR¼4.53, 95% CI 2.03 to 10.1, p<0.001), independence in IADL and BADL (OR¼9.90, 95% CI 4.51 to 21.7, p<0.001), male gender (OR¼1.89, 95% CI 1.21 to 2.96, p¼0.005) and lesser handicap (trend: OR¼3.47, 95% CI 2.51 to 4.79, p<0.001). Participants’ HRQoL scores tended to be lower when HRQoL assessments were completed by proxy (OR¼0.13, 95% CI 0.06 to 0.31, p<0.001). Conclusion At 7 years post-stroke, 68.8% had died and a substantial proportion of survivors had poor HRQoL. Factors such as handicap, BADL and IADL could be targeted to improve HRQoL in long-term survivors of stroke.

Item Details

Item Type:Refereed Article
Research Division:Medical and Health Sciences
Research Group:Public Health and Health Services
Research Field:Epidemiology
Objective Division:Health
Objective Group:Clinical Health (Organs, Diseases and Abnormal Conditions)
Objective Field:Cardiovascular System and Diseases
Author:Gall, SL (Dr Seana Gall)
ID Code:73048
Year Published:2011
Web of Science® Times Cited:25
Deposited By:Menzies Institute for Medical Research
Deposited On:2011-09-08
Last Modified:2014-10-14
Downloads:0

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