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Growth factors and trefoil peptides in gastrointestinal health and disease
journal contribution
posted on 2023-05-17, 08:07 authored by Playford, RJ, Ghosh, S, Mahmood, APeptide growth factors are a fascinating group of molecules with diverse effects. Recent developments have allowed us to gain a much greater insight into their pathophysiological functions. In addition, the development of recombinant peptide technology, monoclonal antibody production and both artificial small molecule receptor agonists and inhibitors now allows us to use these factors for the treatment of multiple conditions including gastrointestinal malignancy (particularly colonic carcinoma), short bowel syndrome (where factors such as growth hormone, epidermal growth factor and glucagons-like peptide 2 show particular promise), and inflammatory bowel disease. © 2004 Elsevier Ltd. All rights reserved.
History
Publication title
Current Opinion in PharmacologyVolume
4Issue
6Pagination
567-571ISSN
1471-4892Department/School
College Office - College of Health and MedicinePublisher
Elsevier Sci LtdPlace of publication
The Boulevard, Langford Lane, Kidlington, Oxford, England, Oxon, Ox5 1GbRepository Status
- Restricted