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Growth factors and trefoil peptides in gastrointestinal health and disease


Playford, RJ and Ghosh, S and Mahmood, A, Growth factors and trefoil peptides in gastrointestinal health and disease, Current Opinion in Pharmacology, 4, (6) pp. 567-571. ISSN 1471-4892 (2004) [Refereed Article]

DOI: doi:10.1016/j.coph.2004.05.004


Peptide growth factors are a fascinating group of molecules with diverse effects. Recent developments have allowed us to gain a much greater insight into their pathophysiological functions. In addition, the development of recombinant peptide technology, monoclonal antibody production and both artificial small molecule receptor agonists and inhibitors now allows us to use these factors for the treatment of multiple conditions including gastrointestinal malignancy (particularly colonic carcinoma), short bowel syndrome (where factors such as growth hormone, epidermal growth factor and glucagons-like peptide 2 show particular promise), and inflammatory bowel disease. © 2004 Elsevier Ltd. All rights reserved.

Item Details

Item Type:Refereed Article
Research Division:Biomedical and Clinical Sciences
Research Group:Clinical sciences
Research Field:Gastroenterology and hepatology
Objective Division:Health
Objective Group:Clinical health
Objective Field:Clinical health not elsewhere classified
UTAS Author:Playford, RJ (Professor Ray Playford)
ID Code:72918
Year Published:2004
Web of Science® Times Cited:18
Deposited By:Research Division
Deposited On:2011-09-05
Last Modified:2011-09-05

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