Pantoprazole, Prout and the proton pump

Pantoprazole is a proton pump inhibitor which has recertify had its clinical license extended to include maintenance therapy for the treatment of reflux oesophagitis, Heticobacter pylori eradication and short-term intravenous administration. This article reviews the history of gastric acid secretion and examines the role of proton pump inhibitors, particularly pantoprazole, in the treatment of acid-related disorders.