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Airway Remodeling in Chronic Obstructive Pulmonary Disease (COPD), a Review
Citation
Soltani , A and Sohal, SS and Reid, D and Wood-Baker, R and Walters, EH, Airway Remodeling in Chronic Obstructive Pulmonary Disease (COPD), a Review, Annals of Respiratory Medicine pp. Epub. (2013) [Review Several Works]
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Abstract
Chronic obstructive pulmonary disease (COPD) is a major cause of chronic disability and mortality worldwide. Pathologically, it is a
complex disease involving structural changes in lung parenchyma, airways, and vessels. Tissue remodeling is an integral part of COPD;
nevertheless, published data on airway remodeling in particular in COPD are very limited. This review has summarized the available literature
published during the last decade on structural changes in the airway component of the disease informed by major older publications.
Available data show that COPD is quite different from asthma in regards to airway remodeling even when significant bronchodilator
responses are present. The potential mechanisms of remodeling in COPD and its potential relationship with lung cancer are discussed.
Item Details
| Item Type: | Review Several Works |
|---|---|
| Research Division: | Biomedical and Clinical Sciences |
| Research Group: | Cardiovascular medicine and haematology |
| Research Field: | Respiratory diseases |
| Objective Division: | Health |
| Objective Group: | Clinical health |
| Objective Field: | Clinical health not elsewhere classified |
| UTAS Author: | Soltani , A (Dr Amir Soltani Abhari) |
| UTAS Author: | Sohal, SS (Dr Sukhwinder Sohal) |
| UTAS Author: | Reid, D (Dr David Reid) |
| UTAS Author: | Wood-Baker, R (Professor Richard Wood-Baker) |
| UTAS Author: | Walters, EH (Professor Haydn Walters) |
| ID Code: | 72616 |
| Year Published: | 2013 |
| Deposited By: | Medicine |
| Deposited On: | 2011-08-29 |
| Last Modified: | 2014-02-13 |
| Downloads: | 3 View Download Statistics |
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