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Airway Remodeling in Chronic Obstructive Pulmonary Disease (COPD), a Review


Soltani , A and Sohal, SS and Reid, D and Wood-Baker, R and Walters, EH, Airway Remodeling in Chronic Obstructive Pulmonary Disease (COPD), a Review, Annals of Respiratory Medicine pp. Epub. (2013) [Review Several Works]

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Chronic obstructive pulmonary disease (COPD) is a major cause of chronic disability and mortality worldwide. Pathologically, it is a complex disease involving structural changes in lung parenchyma, airways, and vessels. Tissue remodeling is an integral part of COPD; nevertheless, published data on airway remodeling in particular in COPD are very limited. This review has summarized the available literature published during the last decade on structural changes in the airway component of the disease informed by major older publications. Available data show that COPD is quite different from asthma in regards to airway remodeling even when significant bronchodilator responses are present. The potential mechanisms of remodeling in COPD and its potential relationship with lung cancer are discussed.

Item Details

Item Type:Review Several Works
Research Division:Biomedical and Clinical Sciences
Research Group:Cardiovascular medicine and haematology
Research Field:Respiratory diseases
Objective Division:Health
Objective Group:Clinical health
Objective Field:Clinical health not elsewhere classified
UTAS Author:Soltani , A (Dr Amir Soltani Abhari)
UTAS Author:Sohal, SS (Dr Sukhwinder Sohal)
UTAS Author:Reid, D (Dr David Reid)
UTAS Author:Wood-Baker, R (Professor Richard Wood-Baker)
UTAS Author:Walters, EH (Professor Haydn Walters)
ID Code:72616
Year Published:2013
Deposited By:Medicine
Deposited On:2011-08-29
Last Modified:2014-02-13
Downloads:3 View Download Statistics

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