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Tumor necrosis factor: a master-regulator of leukocyte movement


Sedgwick, JD and Riminton, DS and Cyster, JG and Korner, H, Tumor necrosis factor: a master-regulator of leukocyte movement, Immunology Today, 21, (3) pp. 110-113. ISSN 0167-5699 (2000) [Refereed Article]

DOI: doi:10.1016/S0167-5699(99)01573-X


Tumor necrosis factor (TNF)-mediated activities are potentially numerous, although in TNF-deficient (-/-) mice, altered spatial orientation of leukocytes within tissues is the predominant phenotype. Here, we propose that TNF plays a fundamental role in the control of leukocyte movement by virtue of a pivotal role in regulation of chemokine expression.

Item Details

Item Type:Refereed Article
Research Division:Biomedical and Clinical Sciences
Research Group:Immunology
Research Field:Immunology not elsewhere classified
Objective Division:Health
Objective Group:Clinical health
Objective Field:Clinical health not elsewhere classified
UTAS Author:Korner, H (Professor Heinrich Korner)
ID Code:72572
Year Published:2000
Web of Science® Times Cited:189
Deposited By:Research Division
Deposited On:2011-08-29
Last Modified:2011-08-29

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