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Tumor necrosis factor: a master-regulator of leukocyte movement
Citation
Sedgwick, JD and Riminton, DS and Cyster, JG and Korner, H, Tumor necrosis factor: a master-regulator of leukocyte movement, Immunology Today, 21, (3) pp. 110-113. ISSN 0167-5699 (2000) [Refereed Article]
DOI: doi:10.1016/S0167-5699(99)01573-X
Abstract
Tumor necrosis factor (TNF)-mediated activities are potentially numerous, although in TNF-deficient (-/-) mice, altered spatial orientation of leukocytes within tissues is the predominant phenotype. Here, we propose that TNF plays a fundamental role in the control of leukocyte movement by virtue of a pivotal role in regulation of chemokine expression.
Item Details
| Item Type: | Refereed Article |
|---|---|
| Research Division: | Medical and Health Sciences |
| Research Group: | Immunology |
| Research Field: | Immunology not elsewhere classified |
| Objective Division: | Health |
| Objective Group: | Clinical Health (Organs, Diseases and Abnormal Conditions) |
| Objective Field: | Infectious Diseases |
| Author: | Korner, H (Professor Heinrich Korner) |
| ID Code: | 72572 |
| Year Published: | 2000 |
| Web of Science® Times Cited: | 172 |
| Deposited By: | Research Division |
| Deposited On: | 2011-08-29 |
| Last Modified: | 2011-08-29 |
| Downloads: | 0 |
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