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Background/Objectives: There is inconsistent evidence regarding the association between moderate alcohol consumption and bone mineral density (BMD). The aim of this study was to describe the associations between total and beverage-specific alcohol intake and bone loss in older men and women. Subject/Methods: A total of 862 randomly selected subjects (mean age 63 years, range 51–81, 51% men) were studied at baseline and 2 years later. BMD was assessed by dual-energy X-ray absorptiometry. Beverage specific and total alcohol intake was assessed by food-frequency questionnaire. Falls risk was determined using the short form Physiological Profile Assessment. Incident fractures were ascertained by questionnaire. Results: Total alcohol intake in men positively predicted change in BMD at the lumbar spine and hip (b¼0.008% and 0.006% per year per gram, Po0.05) after adjustment for confounders, but there was no significant association between alcohol intake and change in BMD in women. Lumbar spine BMD at baseline was negatively associated with frequency of spirits/liquor drinking in men (b¼0.01 g/cm2 per category, P¼0.045) and was positively associated with frequency of beer drinking (low alcohol) in women (b¼0.034 g/cm2 per category, P¼0.002). Change in lumbar spine BMD was positively associated with the frequency of red wine drinking in men (b¼0.08% per year per class, P¼0.046). Neither beverage-specific nor total alcohol intake was associated with falls risk or fracture. Conclusions: Alcohol intake especially red wine might prevent bone loss in older men but not women, whereas low-alcohol beer may be protective in women and spirits/liquor may be deleterious in men.

Item Type:	Refereed Article
Keywords:	bone mineral density; ethanol; alcoholic beverages; longitudinal studies
Research Division:	Biomedical and Clinical Sciences
Research Group:	Clinical sciences
Research Field:	Rheumatology and arthritis
Objective Division:	Health
Objective Group:	Clinical health
Objective Field:	Clinical health not elsewhere classified
UTAS Author:	Yin, J (Dr Jing Yin)
UTAS Author:	Winzenberg, T (Professor Tania Winzenberg)
UTAS Author:	Quinn, S (Mrs Sara Quinn)
UTAS Author:	Jones, G (Professor Graeme Jones)
ID Code:	72186
Year Published:	2011
Web of Science® Times Cited:	10
Deposited By:	Menzies Institute for Medical Research
Deposited On:	2011-08-23
Last Modified:	2017-11-01
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