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Obstetric and Anesthetic Management of Severe Congenital Myasthenia Syndrome

Citation

Terblanche, N and Maxwell, C and Keunen, J and Carvalho, JCA, Obstetric and Anesthetic Management of Severe Congenital Myasthenia Syndrome, Anesthesia and Analgesia, 107, (4) pp. 1313-1315. ISSN 0003-2999 (2008) [Refereed Article]

Copyright Statement

Copyright 2008 International Anesthesia Research Society

DOI: doi:10.1213/ane.0b013e3181823d11

Abstract

The congenital myasthenia syndromes form a heterogeneous group of genetic diseases characterized by defective neuromuscular transmission. Although they have muscle fatigability in common with the acquired immune myasthenia syndrome, there are important pathophysiological, diagnostic, management and progression pattern differences between them. We report the management of a 28-yr-old patient with longstanding congenital myasthenia syndromes, who underwent an elective cesarean delivery under spinal anesthesia. Muscle imbalance plus weakness-related scoliosis and chronic respiratory failure complicated her management. Ultrasonography was used to facilitate the spinal anesthetic. Intraoperative noninvasive positive pressure ventilation maintained lung volumes effectively and prevented deterioration in respiratory function. © 2008 International Anesthesia Research Society.

Item Details

Item Type:Refereed Article
Research Division:Medical and Health Sciences
Research Group:Paediatrics and Reproductive Medicine
Research Field:Obstetrics and Gynaecology
Objective Division:Health
Objective Group:Specific Population Health (excl. Indigenous Health)
Objective Field:Women's Health
Author:Terblanche, N (Dr Nico Terblanche)
ID Code:72151
Year Published:2008
Web of Science® Times Cited:4
Deposited By:Menzies Institute for Medical Research
Deposited On:2011-08-23
Last Modified:2017-04-10
Downloads:0

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