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Dysautonomia and heart rate variability following severe traumatic brain injury

Citation

Baguley, IJ and Heriseanu, RE and Felmingham, KL and Cameron, ID, Dysautonomia and heart rate variability following severe traumatic brain injury, Brain Injury, 20, (4) pp. 437-444. ISSN 0269-9052 (2006) [Refereed Article]


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Copyright Statement

Copyright © 2006 Taylor & Francis The definitive published version is available online at: http://www.tandf.co.uk/journals

DOI: doi:10.1080/02699050600664715

Abstract

Primary objective: To investigate disconnection theories postulated as the cause of dysautonomia following severe traumatic brain injury (TBI) through analysis of heart rate variability (HRV). Methods and procedures: Data were collected on age-matched subjects with and without dysautonomia (eight subjects in each group) and 16 non-injured controls. Data included injury details, continuous electrocardiograph recordings and rehabilitation outcome. Main outcomes and results: The TBI group revealed significant differences in HRV parameters both compared to controls and between dysautonomic and non-dysautonomic subjects. Additionally, HRV parameters for dysautonomic subjects showed evidence of an uncoupling of the normal relationship between heart rate and sympathetic/parasympathetic balance. HRV changes persisted for the dysautonomia group for a mean of 14 months post-injury. Conclusions: Dysautonomic subjects revealed prolonged uncoupling of heart rate and HRV parameters compared to non-dysautonomic subjects and controls. These findings represent direct pathophysiological evidence supporting the disconnection theory postulated to produce dysautonomia following TBI.

Item Details

Item Type:Refereed Article
Keywords:Traumatic brain injury, dysautonomia, heart rate variability
Research Division:Psychology and Cognitive Sciences
Research Group:Psychology
Research Field:Biological Psychology (Neuropsychology, Psychopharmacology, Physiological Psychology)
Objective Division:Health
Objective Group:Clinical Health (Organs, Diseases and Abnormal Conditions)
Objective Field:Clinical Health (Organs, Diseases and Abnormal Conditions) not elsewhere classified
Author:Felmingham, KL (Professor Kim Felmingham)
ID Code:72136
Year Published:2006
Web of Science® Times Cited:62
Deposited By:Psychology
Deposited On:2011-08-22
Last Modified:2011-11-04
Downloads:1 View Download Statistics

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