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Masked hypertension is 'unmasked' by low-intensity exercise blood pressure

Citation

Schultz, MG and Hare, JL and Marwick, TH and Stowasser, M and Sharman, JE, Masked hypertension is 'unmasked' by low-intensity exercise blood pressure, Blood Pressure, 20, (5) pp. 284-289. ISSN 0803-7051 (2011) [Refereed Article]


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Copyright Statement

Copyright 2011 Scandinavian Foundation for Cardiovascular Research

DOI: doi:10.3109/08037051.2011.566251

Abstract

Purpose: Masked hypertension (MH) independently predicts mortality but cannot be diagnosed from clinic blood pressure (BP) taken under resting conditions. We sought to determine if MH could be identifi ed from BP taken during a single bout of low-intensity exercise. Methods. BP was recorded at rest and during brief low-level cycling exercise (60 70% of agepredicted maximal heart rate) in 75 untreated subjects with a hypertensive response to exercise (aged 54  9 years). All subjects underwent 24-h ambulatory BP monitoring (ABPM) and MH was defi ned as clinic BP  140/90 mmHg and ABPM BP  130/80 mmHg. Results. There were 42 (56%) patients with MH, and at rest systolic (SBP) was higher in subjects with MH compared with those without MH (127  9 vs 120  9 mmHg; p  0.05). During exercise, MH subjects had signifi cantly higher SBP (188  22 vs 168  15 mmHg; p  0.05), with a greater change from baseline (61  21 vs 48  15 mmHg; p  0.05). Low-level exercise SBP was independently associated with MH, and if  175 mmHg, identifi ed MH with 74% sensitivity and 67% specifi city ( p  0.001). Conclusion. MH can be identifi ed in untreated individuals from low-intensity exercise SBP. Further research on the diagnostic value of BP during early phases of exercise stress testing is needed.

Item Details

Item Type:Refereed Article
Keywords:Blood pressure, exercise, hypertension, masked hypertension
Research Division:Medical and Health Sciences
Research Group:Cardiorespiratory Medicine and Haematology
Research Field:Cardiology (incl. Cardiovascular Diseases)
Objective Division:Health
Objective Group:Clinical Health (Organs, Diseases and Abnormal Conditions)
Objective Field:Cardiovascular System and Diseases
Author:Schultz, MG (Dr Martin Schultz)
Author:Marwick, TH (Professor Tom Marwick)
Author:Sharman, JE (Professor James Sharman)
ID Code:70988
Year Published:2011
Web of Science® Times Cited:26
Deposited By:Menzies Institute for Medical Research
Deposited On:2011-07-06
Last Modified:2014-05-05
Downloads:4 View Download Statistics

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