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Masked hypertension is 'unmasked' by low-intensity exercise blood pressure


Schultz, MG and Hare, JL and Marwick, TH and Stowasser, M and Sharman, JE, Masked hypertension is 'unmasked' by low-intensity exercise blood pressure, Blood Pressure, 20, (5) pp. 284-289. ISSN 0803-7051 (2011) [Refereed Article]

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Copyright Statement

Copyright 2011 Scandinavian Foundation for Cardiovascular Research

DOI: doi:10.3109/08037051.2011.566251


Purpose: Masked hypertension (MH) independently predicts mortality but cannot be diagnosed from clinic blood pressure (BP) taken under resting conditions. We sought to determine if MH could be identified from BP taken during a single bout of low-intensity exercise. Methods. BP was recorded at rest and during brief low-level cycling exercise (60 - 70% of age predicted maximal heart rate) in 75 untreated subjects with a hypertensive response to exercise (aged 54 +- 9 years). All subjects underwent 24-h ambulatory BP monitoring (ABPM) and MH was defined as clinic BP < 140/90 mmHg and ABPM BP ≥ 130/80 mmHg. Results. There were 42 (56%) patients with MH, and at rest systolic (SBP) was higher in subjects with MH compared with those without MH (127 +- 9 vs 120 +- 9 mmHg; p < 0.05). During exercise, MH subjects had significantly higher SBP (188 +- 22 vs 168 +- 15 mmHg; p < 0.05), with a greater change from baseline (61 +- 21 vs 48 +- 15 mmHg; p < 0.05). Low-level exercise SBP was independently associated with MH, and if >= 175 mmHg, identified MH with 74% sensitivity and 67% specificity (p < 0.001). Conclusion. MH can be identified in untreated individuals from low-intensity exercise SBP. Further research on the diagnostic value of BP during early phases of exercise stress testing is needed.

Item Details

Item Type:Refereed Article
Keywords:Blood pressure, exercise, hypertension, masked hypertension
Research Division:Biomedical and Clinical Sciences
Research Group:Cardiovascular medicine and haematology
Research Field:Cardiology (incl. cardiovascular diseases)
Objective Division:Health
Objective Group:Clinical health
Objective Field:Clinical health not elsewhere classified
UTAS Author:Schultz, MG (Dr Martin Schultz)
UTAS Author:Marwick, TH (Professor Tom Marwick)
UTAS Author:Sharman, JE (Professor James Sharman)
ID Code:70988
Year Published:2011
Web of Science® Times Cited:56
Deposited By:Menzies Institute for Medical Research
Deposited On:2011-07-06
Last Modified:2022-11-21
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