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Masked hypertension is 'unmasked' by low-intensity exercise blood pressure
journal contribution
posted on 2023-05-17, 06:44 authored by Martin SchultzMartin Schultz, Hare, JL, Thomas MarwickThomas Marwick, Stowasser, M, James SharmanJames SharmanPurpose: Masked hypertension (MH) independently predicts mortality but cannot be diagnosed from clinic blood pressure (BP) taken under resting conditions. We sought to determine if MH could be identified from BP taken during a single bout of low-intensity exercise. Methods. BP was recorded at rest and during brief low-level cycling exercise (60 - 70% of age predicted maximal heart rate) in 75 untreated subjects with a hypertensive response to exercise (aged 54 +- 9 years). All subjects underwent 24-h ambulatory BP monitoring (ABPM) and MH was defined as clinic BP < 140/90 mmHg and ABPM BP ≥ 130/80 mmHg. Results. There were 42 (56%) patients with MH, and at rest systolic (SBP) was higher in subjects with MH compared with those without MH (127 +- 9 vs 120 +- 9 mmHg; p < 0.05). During exercise, MH subjects had significantly higher SBP (188 +- 22 vs 168 +- 15 mmHg; p < 0.05), with a greater change from baseline (61 +- 21 vs 48 +- 15 mmHg; p < 0.05). Low-level exercise SBP was independently associated with MH, and if >= 175 mmHg, identified MH with 74% sensitivity and 67% specificity (p < 0.001). Conclusion. MH can be identified in untreated individuals from low-intensity exercise SBP. Further research on the diagnostic value of BP during early phases of exercise stress testing is needed.
History
Publication title
Blood PressureVolume
20Issue
5Pagination
284-289ISSN
0803-7051Department/School
Menzies Institute for Medical ResearchPublisher
Taylor & Francis AsPlace of publication
Cort Adelersgt 17, Po Box 2562, Solli, Oslo, Norway, 0202Rights statement
Copyright 2011 Scandinavian Foundation for Cardiovascular ResearchRepository Status
- Restricted