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Investigating the potential of selected natural compounds to increase the potency of pyrethrum against house flies Musca domestica (Diptera: Muscidae)


Joffe, T and Gunning, RV and Allen, GR and Kristensen, M and Alptekin, S and Field, LM and Moores, GD, Investigating the potential of selected natural compounds to increase the potency of pyrethrum against house flies Musca domestica (Diptera: Muscidae), Pest Management Science, 68, (2) pp. 178-184. ISSN 1526-498X (2012) [Refereed Article]

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DOI: doi:10.1002/ps.2241


Background: A study was undertaken to determine the efficacy of seven natural compounds compared with piperonyl butoxide (PBO) in synergising pyrethrum, with the intention of formulating an effective natural synergist with pyrethrum for use in the organic cropmarket.

Results: Discriminating dose bioassays showed PBO to be significantly more effective at synergising pyrethrum in houseflies than the seven natural compounds tested, causing 100% mortality in insecticide-susceptible WHO and resistant 381zb strains of housefly. The most effective natural synergists against WHO houseflies were dillapiole oil, grapefruit oil and parsley seed oil, with 59, 50 and 41% mortality respectively, compared with 18% mortality with unsynergised pyrethrum. Against 381zb houseflies, the most effective natural synergists were parsley seed oil and dillapiole oil. Esterase inhibition by the natural compounds and PBO in vitro showed no correlationwith pyrethrum synergism in vivo,whereas the inhibition of oxidases in vitro more closely correlated with pyrethrum synergism in vivo.

Conclusion: Dillapiole oil and parsley seed oil showed the greatest potential as pyrethrum synergists. PBO remained the most effective synergist, possibly owing to its surfactant properties, enhancing penetration of pyrethrins. The results suggest the involvement of oxidases in pyrethroid resistance in houseflies, with the efficacy of synergists showing a high correlation with inhibition of oxidases.

Item Details

Item Type:Refereed Article
Keywords:esterases, oxidases, bioassays, synergism, pyrethrum, Musca domestica
Research Division:Agricultural, Veterinary and Food Sciences
Research Group:Crop and pasture production
Research Field:Crop and pasture protection (incl. pests, diseases and weeds)
Objective Division:Plant Production and Plant Primary Products
Objective Group:Industrial crops
Objective Field:Cotton
UTAS Author:Joffe, T (Ms Tanya Joffe)
UTAS Author:Allen, GR (Associate Professor Geoff Allen)
ID Code:70073
Year Published:2012
Web of Science® Times Cited:28
Deposited By:Agricultural Science
Deposited On:2011-05-30
Last Modified:2015-07-13
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