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Drug-related problems identified in post-discharge medication reviews for patients taking warfarin
Citation
Stafford, L and Stafford, A and Hughes, J and Angley, M and Bereznicki, L and Peterson, G, Drug-related problems identified in post-discharge medication reviews for patients taking warfarin, International Journal of Clinical Pharmacy, 33, (4) pp. 621-626. ISSN 2210-7703 (2011) [Refereed Article]
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Copyright Statement
The final publication is available at http://www.springerlink.com
DOI: doi:10.1007/s11096-011-9515-0
Abstract
Objective To characterise the nature of the
drug-related problems with warfarin therapy identified in
pharmacist-conducted medication reviews during a collaborative
post-discharge warfarin management service,
with a focus on potentially serious drug interactions. Setting
Australian community pharmacy practice. Method
Medication review reports submitted by pharmacists to
patients’ general practitioners as part of the service were
reviewed and the type and clinical significance of the
warfarin-associated drug-related problems, and the pharmacists’
recommendations were classified. The prevalence
of prescribing of ‘potentially hazardous’ warfarin drug
interactions was investigated and compared with the frequency
of documentation of these interactions in the
medication review reports. Main outcome measure The
number and nature of warfarin-associated drug-related
problems identified and the rate of documentation of
‘potentially hazardous’ warfarin drug interactions in the
reports from pharmacist-conducted medication reviews.
Results A total of 157 warfarin-associated drug-related
problems were documented in 109 medication review
reports (mean 1.4 per patient, 95% CI 1.3–1.6, range 0–5).
Drug selection and Education or information were the most
commonly identified warfarin-associated drug-related
problems; most drug-related problems were of moderate
clinical significance. Eight of 23 potentially serious warfarin
drug interactions (34.8%) were identified in the
medication review reports. Conclusion Pharmacists
addressing drug selection and warfarin education drugrelated
problems during medication reviews may have
contributed to the positive outcomes of the post-discharge
service. Warfarin drug interactions were frequently identified;
however, well-recognised potentially hazardous
interactions were under-reported. Improved communication
along the continuum of care would permit improved
targeting of drug-related problem reporting, especially in
relation to preventable drug interactions.
Item Details
Item Type: | Refereed Article |
---|---|
Keywords: | Anticoagulants Australia Community pharmacy services Drug interactions Medication review Pharmacists Warfarin |
Research Division: | Medical and Health Sciences |
Research Group: | Pharmacology and Pharmaceutical Sciences |
Research Field: | Clinical Pharmacology and Therapeutics |
Objective Division: | Health |
Objective Group: | Health and Support Services |
Objective Field: | Evaluation of Health Outcomes |
UTAS Author: | Stafford, L (Dr Leanne Chalmers) |
UTAS Author: | Stafford, A (Dr Andrew Stafford) |
UTAS Author: | Hughes, J (Mrs Josie Hughes) |
UTAS Author: | Bereznicki, L (Professor Luke Bereznicki) |
UTAS Author: | Peterson, G (Professor Gregory Peterson) |
ID Code: | 69850 |
Year Published: | 2011 |
Web of Science® Times Cited: | 13 |
Deposited By: | Pharmacy |
Deposited On: | 2011-05-23 |
Last Modified: | 2017-11-02 |
Downloads: | 3 View Download Statistics |
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