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A comparison of Etest, M.I.C.Evaluator strips and CLSI broth microdilution for determining B-lactam antimicrobial susceptibility in Haemophilus influenzae

Citation

Tristram, SG, A comparison of Etest, M.I.C.Evaluator strips and CLSI broth microdilution for determining B-lactam antimicrobial susceptibility in Haemophilus influenzae, Journal of Antimicrobial Chemotherapy, 62, (6) pp. 1464-1466. ISSN 0305-7453 (2008) [Refereed Article]

DOI: doi:10.1093/jac/dkn365

Abstract

β-Lactamase-positive ampicillin-resistant (BLPAR) strains of Haemophilus influenzae generally have relatively high ampicillin MICs, but remain susceptible to cephalosporins and co-amoxiclav. β-Lactamase-negative ampicillin-resistant (BLNAR) strains, on the other hand, have relatively low ampicillin MICs and low levels of resistance or decreased susceptibility to cephalosporins and co-amoxiclav due to altered PBP3. Some strains have both β-lactamase and altered PBP3: these β-lactamase-positive co-amoxiclav-resistant (BLPACR) strains have relatively high ampicillin MICs due to the β-lactamase and low MICs of other β-lactam antibiotics associated with altered PBP3.

Item Details

Item Type:Refereed Article
Research Division:Medical and Health Sciences
Research Group:Medical Microbiology
Research Field:Medical Bacteriology
Objective Division:Health
Objective Group:Clinical Health (Organs, Diseases and Abnormal Conditions)
Objective Field:Infectious Diseases
UTAS Author:Tristram, SG (Dr Stephen Tristram)
ID Code:69840
Year Published:2008
Web of Science® Times Cited:5
Deposited By:Health Sciences A
Deposited On:2011-05-23
Last Modified:2018-02-19
Downloads:0

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