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Outcomes of a decision support prompt in community pharmacy dispensing software to promote step-down of proton pump inhibitor therapy


Curtain, C and Peterson, GM and Tenni, P and Bindoff, IK and Williams, M, Outcomes of a decision support prompt in community pharmacy dispensing software to promote step-down of proton pump inhibitor therapy, British Journal of Clinical Pharmacology, 71, (5) pp. 780-784. ISSN 0306-5251 (2011) [Refereed Article]

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DOI: doi:10.1111/j.1365-2125.2010.03890.x


Aim: To evaluate the effect of a computerised decision support prompt regarding high-dose proton pump inhibitor (PPI) therapy on prescribing and medication costs. Method: A prompt activated on dispensing high-dose esomeprazole or pantoprazole was implemented in 73 of 185 pharmacies. Anonymised prescription data and a patient survey were used to determine changes in prescribing and associated medication costs. Results: The pharmacist-recorded PPI intervention rate per 100 high-dose PPI prescriptions was 1.67 for the PPI prompt group and 0.17 for the control group (p < 0.001). During the first 28 days of the trial, 196 interventions resulted in 34 instances of PPI step-down, with 28 of these occurring in PPI prompt pharmacies. Cost savings attributable to the prompt were $7.98 (4.95 GBP) AUD per month per PPI prompt pharmacy compared with $1.05 AUD (0.65 GBP) per control pharmacy. Conclusion: The use of electronic decision support prompts in community pharmacy practice can promote the quality use of medicines.

Item Details

Item Type:Refereed Article
Keywords:Clinical Decision Support Systems, Computer-Assisted Drug Therapy, Clinical Pharmacy Information Systems, Proton Pump Inhibitors, Gastro-oesophageal Reflux/drug therapy, Community Pharmacy
Research Division:Biomedical and Clinical Sciences
Research Group:Pharmacology and pharmaceutical sciences
Research Field:Clinical pharmacy and pharmacy practice
Objective Division:Health
Objective Group:Evaluation of health and support services
Objective Field:Evaluation of health and support services not elsewhere classified
UTAS Author:Curtain, C (Mr Colin Curtain)
UTAS Author:Peterson, GM (Professor Gregory Peterson)
UTAS Author:Tenni, P (Dr Peter Tenni)
UTAS Author:Bindoff, IK (Dr Ivan Bindoff)
UTAS Author:Williams, M (Dr Mackenzie Williams)
ID Code:68868
Year Published:2011
Web of Science® Times Cited:17
Deposited By:Pharmacy
Deposited On:2011-03-28
Last Modified:2017-11-02

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