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Automated volumetric evaluation of stereoscopic disc photography


Xu, J and Ishikawa, H and Wollstein, G and Bilonick, RA and Kagemann, L and Craig, JE and Mackey, DA and Hewitt, AW and Schuman, JS, Automated volumetric evaluation of stereoscopic disc photography, Optics Express, 18, (11) pp. 11347-11359. ISSN 1094-4087 (2010) [Refereed Article]

DOI: doi:10.1364/OE.18.011347


PURPOSE: To develop a fully automated algorithm (AP) to perform a volumetric measure of the optic disc using conventional stereoscopic optic nerve head (ONH) photographs, and to compare algorithm-produced parameters with manual photogrammetry (MP), scanning laser ophthalmoscope (SLO) and optical coherence tomography (OCT) measurements. METHODS: One hundred twenty-two stereoscopic optic disc photographs (61 subjects) were analyzed. Disc area, rim area, cup area, cup/disc area ratio, vertical cup/disc ratio, rim volume and cup volume were automatically computed by the algorithm. Latent variable measurement error models were used to assess measurement reproducibility for the four techniques. RESULTS: AP had better reproducibility for disc area and cup volume and worse reproducibility for cup/disc area ratio and vertical cup/disc ratio, when the measurements were compared to the MP, SLO and OCT methods. CONCLUSION: AP provides a useful technique for an objective quantitative assessment of 3D ONH structures. © 2010 Optical Society of America.

Item Details

Item Type:Refereed Article
Research Division:Biomedical and Clinical Sciences
Research Group:Ophthalmology and optometry
Research Field:Vision science
Objective Division:Health
Objective Group:Clinical health
Objective Field:Clinical health not elsewhere classified
UTAS Author:Mackey, DA (Professor David Mackey)
UTAS Author:Hewitt, AW (Professor Alex Hewitt)
ID Code:67895
Year Published:2010
Web of Science® Times Cited:6
Deposited By:Medicine
Deposited On:2011-03-08
Last Modified:2014-09-26

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