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Regulation of the gibberellin pathway by auxin and DELLA proteins


O'Neill, DP and Davidson, SE and Clarke, VC and Yamauchi, Y and Yamaguchi, S and Kamiya, Y and Reid, JB and Ross, JJ, Regulation of the gibberellin pathway by auxin and DELLA proteins, Planta, 232, (5) pp. 1141-1149. ISSN 0032-0935 (2010) [Refereed Article]

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DOI: doi:10.1007/s00425-010-1248-0


The synthesis and deactivation of bioactive gibberellins (GA) are regulated by auxin and by GA signalling. The effect of GA on its own pathway is mediated by DELLA proteins. Like auxin, the DELLAs promote GA synthesis and inhibit its deactivation. Here, we investigate the relationships between auxin and DELLA regulation of the GA pathway in stems, using a pea double mutant that is deficient in DELLA proteins. In general terms our results demonstrate that auxin and DELLAs independently regulate the GA pathway, contrary to some previous suggestions. The extent to which DELLA regulation was able to counteract the effects of auxin regulation varied from gene to gene. For Mendelís LE gene (PsGA3ox1) no counteraction was observed. However, for another synthesis gene, a GA 20-oxidase, the effect of auxin was weak and in WT plants appeared to be completely over-ridden by DELLA regulation. For a key GA deactivation (2-oxidase) gene, PsGA2ox1, the up-regulation induced by auxin deficiency was reduced to some extent by DELLA regulation. A second pea 2-oxidase gene, PsGA2ox2, was up-regulated by auxin, in a DELLA-independent manner. In Arabidopsis also, one 2-oxidase gene was down-regulated by auxin while another was up-regulated. Monitoring the metabolism pattern of GA20 showed that in Arabidopsis, as in pea, auxin can promote the accumulation of bioactive GA.

Item Details

Item Type:Refereed Article
Keywords:Arabidopsis, Auxin, DELLA protein, Gibberellin, Pisum
Research Division:Biological Sciences
Research Group:Plant biology
Research Field:Plant physiology
Objective Division:Plant Production and Plant Primary Products
Objective Group:Horticultural crops
Objective Field:Horticultural crops not elsewhere classified
UTAS Author:Davidson, SE (Dr Sandra Davidson)
UTAS Author:Reid, JB (Professor Jim Reid)
UTAS Author:Ross, JJ (Associate Professor John Ross)
ID Code:67343
Year Published:2010
Web of Science® Times Cited:48
Deposited By:Plant Science
Deposited On:2011-03-02
Last Modified:2011-05-12
Downloads:2 View Download Statistics

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