eCite Digital Repository

Evaluation of a community pharmacy-based intervention for improving patient adherence to antihypertensives: a randomised controlled trial

Citation

Lau, R and Stewart, K and McNamara, KP and Jackson, SL and Hughes, JD and Peterson, GM and Bortoletto, DA and McDowell, J and Bailey, MJ and Hsueh, A and George, J, Evaluation of a community pharmacy-based intervention for improving patient adherence to antihypertensives: a randomised controlled trial, BMC Health Services Research, 10, (34) EJ ISSN 1472-6963 (2010) [Contribution to Refereed Journal]

PDF
146Kb
  

Copyright Statement

Copyright © 2010 Lau et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The electronic version of this article is the complete one and can be found online at: http://www.biomedcentral.com/1472-6963/10/34

Official URL: http://www.biomedcentral.com/1472-6963/10/34

DOI: doi:10.1186/1472-6963-10-34

Abstract

Background The majority of patients using antihypertensive medications fail to achieve their recommended target blood pressure. Poor daily adherence with medication regimens and a lack of persistence with medication use are two of the major reasons for failure to reach target blood pressure. There is no single intervention to improve adherence with antihypertensives that is consistently effective. Community pharmacists are in an ideal position to promote adherence to chronic medications. This study aims to test a specific intervention package that could be integrated into the community pharmacy workflow to enable pharmacists to improve patient adherence and/or persistence with antihypertensive medications - Hypertension Adherence Program in Pharmacy (HAPPY). Methods/Design The HAPPY trial is a multi-centre prospective randomised controlled trial. Fifty-six pharmacies have been recruited from three Australian states. To identify potential patients, a software application (MedeMine CVD) extracted data from a community pharmacy dispensing software system (FRED Dispense®). The pharmacies have been randomised to either 'Pharmacist Care Group' (PCG) or 'Usual Care Group' (UCG). To check for 'Hawthorne effect' in the UCG, a third group of patients 'Hidden Control Group' (HCG) will be identified in the UCG pharmacies, which will be made known to the pharmacists at the end of six months. Each study group requires 182 patients. Data will be collected at baseline, three and six months in the PCG and at baseline and six months in the UCG. Changes in patient adherence and persistence at the end of six months will be measured using the self-reported Morisky score, the Tool for Adherence Behaviour Screening and medication refill data. Discussion To our knowledge, this is the first research testing a comprehensive package of evidence-based interventions that could be integrated into the community pharmacy workflow to enable pharmacists to improve patient adherence and/or persistence with antihypertensive medications. The unique features of the HAPPY trial include the use of MedeMine CVD to identify patients who could potentially benefit from the service, control for the 'Hawthorne effect' in the UCG and the offer of the intervention package at the end of six months to patients in the UCG, a strategy that is expected to improve retention. Trial Registration Australian New Zealand Clinical Trial Registry ACTRN12609000705280

Item Details

Item Type:Contribution to Refereed Journal
Research Division:Medical and Health Sciences
Research Group:Pharmacology and Pharmaceutical Sciences
Research Field:Clinical Pharmacy and Pharmacy Practice
Objective Division:Health
Objective Group:Health and Support Services
Objective Field:Health Policy Evaluation
UTAS Author:Jackson, SL (Dr Shane Jackson)
UTAS Author:Peterson, GM (Professor Gregory Peterson)
ID Code:66468
Year Published:2010
Web of Science® Times Cited:20
Deposited By:Pharmacy
Deposited On:2011-01-27
Last Modified:2011-06-10
Downloads:438 View Download Statistics

Repository Staff Only: item control page