eCite Digital Repository
Oral contraceptive use and bone
Citation
Wei, S and Winzenberg, T and Laslett, LL and Venn, A and Jones, G, Oral contraceptive use and bone, Current Osteoporosis Reports , 9, (1) pp. 6-11. ISSN 1544-2241 (2010) [Refereed Article]
![]() | PDF Restricted - Request a copy 2Mb |
Copyright Statement
The original publication is available at http://www.springerlink.com
Official URL: http://www.springerlink.com
DOI: doi:10.1007/s11914-010-0037-9
Abstract
Sex hormones play a key role in bone homeostasis,
and oral contraceptive (OC) use may affect bone
mass in women. However, the nature of the association
between OC use and bone remains controversial. This
paper critically reviews studies on OC use and bone
published between January 2009 and August 2010. Studies
of OC use and bone mass mainly focus on adolescents or
young adults and showed mixed results. Weak evidence
suggests that OC use has no effect or a beneficial effect on
bone mass, except in women commencing OCs shortly
after menarche, and a consistently negative effect on bone
turnover markers. A limited number of studies have
examined the effect of ultra-low-dose OC (20 μg ethinyl
estradiol) on bone mass in adolescents or young adults, and
present conflicting results. The lack of randomized trials
indicates that further high-quality prospective studies are
required to investigate the effect of OC use on bone mass,
particularly the optimal dose and timing of initiation of OC
use in adolescents requiring contraception.
Item Details
Item Type: | Refereed Article |
---|---|
Keywords: | oral contraceptive, bone mass, fracture, bone turnover marker, adolescent, young adults |
Research Division: | Biomedical and Clinical Sciences |
Research Group: | Clinical sciences |
Research Field: | Rheumatology and arthritis |
Objective Division: | Health |
Objective Group: | Clinical health |
Objective Field: | Clinical health not elsewhere classified |
UTAS Author: | Wei, S (Mrs Shuying Wei) |
UTAS Author: | Winzenberg, T (Professor Tania Winzenberg) |
UTAS Author: | Laslett, LL (Dr Laura Laslett) |
UTAS Author: | Venn, A (Professor Alison Venn) |
UTAS Author: | Jones, G (Professor Graeme Jones) |
ID Code: | 66377 |
Year Published: | 2010 |
Deposited By: | Menzies Institute for Medical Research |
Deposited On: | 2011-01-13 |
Last Modified: | 2013-04-08 |
Downloads: | 2 View Download Statistics |
Repository Staff Only: item control page